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Development of a Predictive Dosing Nomogram to Achieve PK/PD Targets of Amikacin Initial Dose in Critically Ill Patients: A Non-Parametric Approach

French guidelines recommend reaching an amikacin concentration of ≥8 × MIC 1 h after beginning infusion (C(1h)), with MIC = 8 mg/L for probabilistic therapy. We aimed to elaborate a nomogram guiding clinicians in choosing the right first amikacin dose for ICU patients in septic shock. A total of 138...

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Detalles Bibliográficos
Autores principales:	Coste, Anne, Bellouard, Ronan, Deslandes, Guillaume, Jalin, Laurence, Roger, Claire, Ansart, Séverine, Dailly, Eric, Bretonnière, Cédric, Grégoire, Matthieu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854650/ https://www.ncbi.nlm.nih.gov/pubmed/36671324 http://dx.doi.org/10.3390/antibiotics12010123

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