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Uric Acid Deteriorates Load-Free Cell Shortening of Cultured Adult Rat Ventricular Cardiomyocytes via Stimulation of Arginine Turnover

SIMPLE SUMMARY: Uric acid is a metabolite released by cells to detoxify themselves from nitrogen. Unlike other mammalians, hominids, and also birds, lack uricase, an enzyme that catalyzes the transformation of uric acid to allantoin. Therefore, high levels of uric acid accumulate in the plasma of ho...

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Detalles Bibliográficos
Autores principales:	Weber, Martin, Schreckenberg, Rolf, Schlüter, Klaus-Dieter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854662/ https://www.ncbi.nlm.nih.gov/pubmed/36671696 http://dx.doi.org/10.3390/biology12010004

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