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Optical Coherence Tomography Is a Promising Tool for Zebrafish-Based Research—A Review

The zebrafish is an established vertebrae model in the field of biomedical research. With its small size, rapid maturation time and semi-transparency at early development stages, it has proven to be an important animal model, especially for high-throughput studies. Three-dimensional, high-resolution...

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Detalles Bibliográficos
Autores principales: Lichtenegger, Antonia, Baumann, Bernhard, Yasuno, Yoshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854701/
https://www.ncbi.nlm.nih.gov/pubmed/36671577
http://dx.doi.org/10.3390/bioengineering10010005
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author Lichtenegger, Antonia
Baumann, Bernhard
Yasuno, Yoshiaki
author_facet Lichtenegger, Antonia
Baumann, Bernhard
Yasuno, Yoshiaki
author_sort Lichtenegger, Antonia
collection PubMed
description The zebrafish is an established vertebrae model in the field of biomedical research. With its small size, rapid maturation time and semi-transparency at early development stages, it has proven to be an important animal model, especially for high-throughput studies. Three-dimensional, high-resolution, non-destructive and label-free imaging techniques are perfectly suited to investigate these animals over various development stages. Optical coherence tomography (OCT) is an interferometric-based optical imaging technique that has revolutionized the diagnostic possibilities in the field of ophthalmology and has proven to be a powerful tool for many microscopic applications. Recently, OCT found its way into state-of-the-art zebrafish-based research. This review article gives an overview and a discussion of the relevant literature and an outlook for this emerging field.
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spelling pubmed-98547012023-01-21 Optical Coherence Tomography Is a Promising Tool for Zebrafish-Based Research—A Review Lichtenegger, Antonia Baumann, Bernhard Yasuno, Yoshiaki Bioengineering (Basel) Review The zebrafish is an established vertebrae model in the field of biomedical research. With its small size, rapid maturation time and semi-transparency at early development stages, it has proven to be an important animal model, especially for high-throughput studies. Three-dimensional, high-resolution, non-destructive and label-free imaging techniques are perfectly suited to investigate these animals over various development stages. Optical coherence tomography (OCT) is an interferometric-based optical imaging technique that has revolutionized the diagnostic possibilities in the field of ophthalmology and has proven to be a powerful tool for many microscopic applications. Recently, OCT found its way into state-of-the-art zebrafish-based research. This review article gives an overview and a discussion of the relevant literature and an outlook for this emerging field. MDPI 2022-12-20 /pmc/articles/PMC9854701/ /pubmed/36671577 http://dx.doi.org/10.3390/bioengineering10010005 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Lichtenegger, Antonia
Baumann, Bernhard
Yasuno, Yoshiaki
Optical Coherence Tomography Is a Promising Tool for Zebrafish-Based Research—A Review
title Optical Coherence Tomography Is a Promising Tool for Zebrafish-Based Research—A Review
title_full Optical Coherence Tomography Is a Promising Tool for Zebrafish-Based Research—A Review
title_fullStr Optical Coherence Tomography Is a Promising Tool for Zebrafish-Based Research—A Review
title_full_unstemmed Optical Coherence Tomography Is a Promising Tool for Zebrafish-Based Research—A Review
title_short Optical Coherence Tomography Is a Promising Tool for Zebrafish-Based Research—A Review
title_sort optical coherence tomography is a promising tool for zebrafish-based research—a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854701/
https://www.ncbi.nlm.nih.gov/pubmed/36671577
http://dx.doi.org/10.3390/bioengineering10010005
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