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Optical Coherence Tomography Is a Promising Tool for Zebrafish-Based Research—A Review
The zebrafish is an established vertebrae model in the field of biomedical research. With its small size, rapid maturation time and semi-transparency at early development stages, it has proven to be an important animal model, especially for high-throughput studies. Three-dimensional, high-resolution...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854701/ https://www.ncbi.nlm.nih.gov/pubmed/36671577 http://dx.doi.org/10.3390/bioengineering10010005 |
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author | Lichtenegger, Antonia Baumann, Bernhard Yasuno, Yoshiaki |
author_facet | Lichtenegger, Antonia Baumann, Bernhard Yasuno, Yoshiaki |
author_sort | Lichtenegger, Antonia |
collection | PubMed |
description | The zebrafish is an established vertebrae model in the field of biomedical research. With its small size, rapid maturation time and semi-transparency at early development stages, it has proven to be an important animal model, especially for high-throughput studies. Three-dimensional, high-resolution, non-destructive and label-free imaging techniques are perfectly suited to investigate these animals over various development stages. Optical coherence tomography (OCT) is an interferometric-based optical imaging technique that has revolutionized the diagnostic possibilities in the field of ophthalmology and has proven to be a powerful tool for many microscopic applications. Recently, OCT found its way into state-of-the-art zebrafish-based research. This review article gives an overview and a discussion of the relevant literature and an outlook for this emerging field. |
format | Online Article Text |
id | pubmed-9854701 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-98547012023-01-21 Optical Coherence Tomography Is a Promising Tool for Zebrafish-Based Research—A Review Lichtenegger, Antonia Baumann, Bernhard Yasuno, Yoshiaki Bioengineering (Basel) Review The zebrafish is an established vertebrae model in the field of biomedical research. With its small size, rapid maturation time and semi-transparency at early development stages, it has proven to be an important animal model, especially for high-throughput studies. Three-dimensional, high-resolution, non-destructive and label-free imaging techniques are perfectly suited to investigate these animals over various development stages. Optical coherence tomography (OCT) is an interferometric-based optical imaging technique that has revolutionized the diagnostic possibilities in the field of ophthalmology and has proven to be a powerful tool for many microscopic applications. Recently, OCT found its way into state-of-the-art zebrafish-based research. This review article gives an overview and a discussion of the relevant literature and an outlook for this emerging field. MDPI 2022-12-20 /pmc/articles/PMC9854701/ /pubmed/36671577 http://dx.doi.org/10.3390/bioengineering10010005 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Lichtenegger, Antonia Baumann, Bernhard Yasuno, Yoshiaki Optical Coherence Tomography Is a Promising Tool for Zebrafish-Based Research—A Review |
title | Optical Coherence Tomography Is a Promising Tool for Zebrafish-Based Research—A Review |
title_full | Optical Coherence Tomography Is a Promising Tool for Zebrafish-Based Research—A Review |
title_fullStr | Optical Coherence Tomography Is a Promising Tool for Zebrafish-Based Research—A Review |
title_full_unstemmed | Optical Coherence Tomography Is a Promising Tool for Zebrafish-Based Research—A Review |
title_short | Optical Coherence Tomography Is a Promising Tool for Zebrafish-Based Research—A Review |
title_sort | optical coherence tomography is a promising tool for zebrafish-based research—a review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854701/ https://www.ncbi.nlm.nih.gov/pubmed/36671577 http://dx.doi.org/10.3390/bioengineering10010005 |
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