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Continuous Infusion of High Doses of Cefepime in Intensive Care Unit: Assessment of Steady-State Plasma Level and Incidence on Neurotoxicity

Continuous infusion (CI) with high doses of cefepime is recommended in the empirical antimicrobial regimen of critically ill patients with suspected Gram-negative sepsis. This study aimed to determine factors associated with cefepime overdosing and the incidence of cefepime-induced neurotoxicity (CI...

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Detalles Bibliográficos
Autores principales: Jean-Michel, Vanessa, Homey, Corentin, Devos, Patrick, Delannoy, Pierre-Yves, Boussekey, Nicolas, Caulier, Thomas, Leroy, Olivier, Georges, Hugues
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854724/
https://www.ncbi.nlm.nih.gov/pubmed/36671270
http://dx.doi.org/10.3390/antibiotics12010069