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The Importance of Accurate Early Diagnosis and Eradication in Helicobacter pylori Infection: Pictorial Summary Review in Children and Adults

Among the most widespread childhood infections, Helicobacter pylori (H. pylori) develops potentially life-threatening conditions in adults if not appropriately treated. Helicobacter pylori is a common human pathogen that was first described in the stomach many years ago. The discovery of H. pylori w...

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Autores principales: Marginean, Cristina Maria, Cioboata, Ramona, Olteanu, Mihai, Vasile, Corina Maria, Popescu, Mihaela, Popescu, Alin Iulian Silviu, Bondari, Simona, Pirscoveanu, Denisa, Marginean, Iulia Cristina, Iacob, George Alexandru, Popescu, Mihai Daniel, Stanciu, Mihaela, Mitrut, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854763/
https://www.ncbi.nlm.nih.gov/pubmed/36671261
http://dx.doi.org/10.3390/antibiotics12010060
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author Marginean, Cristina Maria
Cioboata, Ramona
Olteanu, Mihai
Vasile, Corina Maria
Popescu, Mihaela
Popescu, Alin Iulian Silviu
Bondari, Simona
Pirscoveanu, Denisa
Marginean, Iulia Cristina
Iacob, George Alexandru
Popescu, Mihai Daniel
Stanciu, Mihaela
Mitrut, Paul
author_facet Marginean, Cristina Maria
Cioboata, Ramona
Olteanu, Mihai
Vasile, Corina Maria
Popescu, Mihaela
Popescu, Alin Iulian Silviu
Bondari, Simona
Pirscoveanu, Denisa
Marginean, Iulia Cristina
Iacob, George Alexandru
Popescu, Mihai Daniel
Stanciu, Mihaela
Mitrut, Paul
author_sort Marginean, Cristina Maria
collection PubMed
description Among the most widespread childhood infections, Helicobacter pylori (H. pylori) develops potentially life-threatening conditions in adults if not appropriately treated. Helicobacter pylori is a common human pathogen that was first described in the stomach many years ago. The discovery of H. pylori was crucial in gastroenterology; this bacterium is associated with chronic gastritis, peptic ulcers, gastric cancer, and lymphoid tissue lymphoma related to the gastric mucosa. Studies published so far estimate that approximately 10% of subjects infected with H. pylori develop a peptic ulcer, and 1–3% of subjects develop gastric cancer. The clinical manifestations are variable and characteristically depend on the individual factors of the host. Various methods of detection and diagnosis of H. pylori infection have been developed, each with advantages, disadvantages, and/or limitations. Available diagnostic tests are usually performed using invasive (endoscopy, biopsy, rapid urease test, cultures, and molecular tests) and noninvasive methods (urea breath test, stool antigen examination, and serological and molecular tests). Although there is extensive accessibility for diagnosing and treating H. pylori infection, the prevalence of antibiotic resistance is not negligible. Thus, numerous studies and meta-analyses are focused on a new orientation of gastroenterologists in diagnosing and treating H. pylori infections. A fascinating perspective hypothesis is the administration of probiotics to reduce H. pylori adhesion to gastric epithelial cells, preventing H. pylori colonization, especially in children, or reinfection with H. pylori in high-risk adult patients.
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spelling pubmed-98547632023-01-21 The Importance of Accurate Early Diagnosis and Eradication in Helicobacter pylori Infection: Pictorial Summary Review in Children and Adults Marginean, Cristina Maria Cioboata, Ramona Olteanu, Mihai Vasile, Corina Maria Popescu, Mihaela Popescu, Alin Iulian Silviu Bondari, Simona Pirscoveanu, Denisa Marginean, Iulia Cristina Iacob, George Alexandru Popescu, Mihai Daniel Stanciu, Mihaela Mitrut, Paul Antibiotics (Basel) Review Among the most widespread childhood infections, Helicobacter pylori (H. pylori) develops potentially life-threatening conditions in adults if not appropriately treated. Helicobacter pylori is a common human pathogen that was first described in the stomach many years ago. The discovery of H. pylori was crucial in gastroenterology; this bacterium is associated with chronic gastritis, peptic ulcers, gastric cancer, and lymphoid tissue lymphoma related to the gastric mucosa. Studies published so far estimate that approximately 10% of subjects infected with H. pylori develop a peptic ulcer, and 1–3% of subjects develop gastric cancer. The clinical manifestations are variable and characteristically depend on the individual factors of the host. Various methods of detection and diagnosis of H. pylori infection have been developed, each with advantages, disadvantages, and/or limitations. Available diagnostic tests are usually performed using invasive (endoscopy, biopsy, rapid urease test, cultures, and molecular tests) and noninvasive methods (urea breath test, stool antigen examination, and serological and molecular tests). Although there is extensive accessibility for diagnosing and treating H. pylori infection, the prevalence of antibiotic resistance is not negligible. Thus, numerous studies and meta-analyses are focused on a new orientation of gastroenterologists in diagnosing and treating H. pylori infections. A fascinating perspective hypothesis is the administration of probiotics to reduce H. pylori adhesion to gastric epithelial cells, preventing H. pylori colonization, especially in children, or reinfection with H. pylori in high-risk adult patients. MDPI 2022-12-29 /pmc/articles/PMC9854763/ /pubmed/36671261 http://dx.doi.org/10.3390/antibiotics12010060 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Marginean, Cristina Maria
Cioboata, Ramona
Olteanu, Mihai
Vasile, Corina Maria
Popescu, Mihaela
Popescu, Alin Iulian Silviu
Bondari, Simona
Pirscoveanu, Denisa
Marginean, Iulia Cristina
Iacob, George Alexandru
Popescu, Mihai Daniel
Stanciu, Mihaela
Mitrut, Paul
The Importance of Accurate Early Diagnosis and Eradication in Helicobacter pylori Infection: Pictorial Summary Review in Children and Adults
title The Importance of Accurate Early Diagnosis and Eradication in Helicobacter pylori Infection: Pictorial Summary Review in Children and Adults
title_full The Importance of Accurate Early Diagnosis and Eradication in Helicobacter pylori Infection: Pictorial Summary Review in Children and Adults
title_fullStr The Importance of Accurate Early Diagnosis and Eradication in Helicobacter pylori Infection: Pictorial Summary Review in Children and Adults
title_full_unstemmed The Importance of Accurate Early Diagnosis and Eradication in Helicobacter pylori Infection: Pictorial Summary Review in Children and Adults
title_short The Importance of Accurate Early Diagnosis and Eradication in Helicobacter pylori Infection: Pictorial Summary Review in Children and Adults
title_sort importance of accurate early diagnosis and eradication in helicobacter pylori infection: pictorial summary review in children and adults
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854763/
https://www.ncbi.nlm.nih.gov/pubmed/36671261
http://dx.doi.org/10.3390/antibiotics12010060
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