Fibroblasts Impair Migration and Antitumor Activity of NK-92 Lymphocytes in a Melanoma-on-Chip Model

Adoptive cell therapy in solid tumors, such as melanoma, is impaired, but little is known about the role that the fibroblasts present in the tumor microenvironment could exert. However, the mechanism at play is not well understood, partly due to the lack of relevant pre-clinical models. Three-dimens...

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Detalles Bibliográficos
Autores principales: Iaia, Ilenia, Brancato, Virginia, Caballero, David, Reis, Rui L., Aglietta, Massimo, Sangiolo, Dario, Kundu, Subhas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854880/
https://www.ncbi.nlm.nih.gov/pubmed/36671624
http://dx.doi.org/10.3390/bioengineering10010052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9854880/
https://www.ncbi.nlm.nih.gov/pubmed/36671624
http://dx.doi.org/10.3390/bioengineering10010052

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