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Recent Advances in Phage-Based Therapeutics for Multi-Drug Resistant Acinetobacter baumannii
Acinetobacter baumannii is an important opportunistic pathogen common in clinical infections. Phage therapy become a hot research field worldwide again after the post-antibiotic era. This review summarizes the important progress of phage treatments for A. baumannii in the last five years, and focus...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855029/ https://www.ncbi.nlm.nih.gov/pubmed/36671607 http://dx.doi.org/10.3390/bioengineering10010035 |
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author | Tan, Yujing Su, Jianhui Fu, Minghui Zhang, Hongmei Zeng, Haiyan |
author_facet | Tan, Yujing Su, Jianhui Fu, Minghui Zhang, Hongmei Zeng, Haiyan |
author_sort | Tan, Yujing |
collection | PubMed |
description | Acinetobacter baumannii is an important opportunistic pathogen common in clinical infections. Phage therapy become a hot research field worldwide again after the post-antibiotic era. This review summarizes the important progress of phage treatments for A. baumannii in the last five years, and focus on the new interesting advances including the combination of phage and other substances (like photosensitizer), and the phage encapsulation (by microparticle, hydrogel) in delivery. We also discuss the remaining challenges and promising directions for phage-based therapy of A. baumannii infection in the future, and the innovative combination of materials in this area may be one promising direction. |
format | Online Article Text |
id | pubmed-9855029 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-98550292023-01-21 Recent Advances in Phage-Based Therapeutics for Multi-Drug Resistant Acinetobacter baumannii Tan, Yujing Su, Jianhui Fu, Minghui Zhang, Hongmei Zeng, Haiyan Bioengineering (Basel) Review Acinetobacter baumannii is an important opportunistic pathogen common in clinical infections. Phage therapy become a hot research field worldwide again after the post-antibiotic era. This review summarizes the important progress of phage treatments for A. baumannii in the last five years, and focus on the new interesting advances including the combination of phage and other substances (like photosensitizer), and the phage encapsulation (by microparticle, hydrogel) in delivery. We also discuss the remaining challenges and promising directions for phage-based therapy of A. baumannii infection in the future, and the innovative combination of materials in this area may be one promising direction. MDPI 2022-12-27 /pmc/articles/PMC9855029/ /pubmed/36671607 http://dx.doi.org/10.3390/bioengineering10010035 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Tan, Yujing Su, Jianhui Fu, Minghui Zhang, Hongmei Zeng, Haiyan Recent Advances in Phage-Based Therapeutics for Multi-Drug Resistant Acinetobacter baumannii |
title | Recent Advances in Phage-Based Therapeutics for Multi-Drug Resistant Acinetobacter baumannii |
title_full | Recent Advances in Phage-Based Therapeutics for Multi-Drug Resistant Acinetobacter baumannii |
title_fullStr | Recent Advances in Phage-Based Therapeutics for Multi-Drug Resistant Acinetobacter baumannii |
title_full_unstemmed | Recent Advances in Phage-Based Therapeutics for Multi-Drug Resistant Acinetobacter baumannii |
title_short | Recent Advances in Phage-Based Therapeutics for Multi-Drug Resistant Acinetobacter baumannii |
title_sort | recent advances in phage-based therapeutics for multi-drug resistant acinetobacter baumannii |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855029/ https://www.ncbi.nlm.nih.gov/pubmed/36671607 http://dx.doi.org/10.3390/bioengineering10010035 |
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