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Recent Advances in Phage-Based Therapeutics for Multi-Drug Resistant Acinetobacter baumannii

Acinetobacter baumannii is an important opportunistic pathogen common in clinical infections. Phage therapy become a hot research field worldwide again after the post-antibiotic era. This review summarizes the important progress of phage treatments for A. baumannii in the last five years, and focus...

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Detalles Bibliográficos
Autores principales: Tan, Yujing, Su, Jianhui, Fu, Minghui, Zhang, Hongmei, Zeng, Haiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855029/
https://www.ncbi.nlm.nih.gov/pubmed/36671607
http://dx.doi.org/10.3390/bioengineering10010035
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author Tan, Yujing
Su, Jianhui
Fu, Minghui
Zhang, Hongmei
Zeng, Haiyan
author_facet Tan, Yujing
Su, Jianhui
Fu, Minghui
Zhang, Hongmei
Zeng, Haiyan
author_sort Tan, Yujing
collection PubMed
description Acinetobacter baumannii is an important opportunistic pathogen common in clinical infections. Phage therapy become a hot research field worldwide again after the post-antibiotic era. This review summarizes the important progress of phage treatments for A. baumannii in the last five years, and focus on the new interesting advances including the combination of phage and other substances (like photosensitizer), and the phage encapsulation (by microparticle, hydrogel) in delivery. We also discuss the remaining challenges and promising directions for phage-based therapy of A. baumannii infection in the future, and the innovative combination of materials in this area may be one promising direction.
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spelling pubmed-98550292023-01-21 Recent Advances in Phage-Based Therapeutics for Multi-Drug Resistant Acinetobacter baumannii Tan, Yujing Su, Jianhui Fu, Minghui Zhang, Hongmei Zeng, Haiyan Bioengineering (Basel) Review Acinetobacter baumannii is an important opportunistic pathogen common in clinical infections. Phage therapy become a hot research field worldwide again after the post-antibiotic era. This review summarizes the important progress of phage treatments for A. baumannii in the last five years, and focus on the new interesting advances including the combination of phage and other substances (like photosensitizer), and the phage encapsulation (by microparticle, hydrogel) in delivery. We also discuss the remaining challenges and promising directions for phage-based therapy of A. baumannii infection in the future, and the innovative combination of materials in this area may be one promising direction. MDPI 2022-12-27 /pmc/articles/PMC9855029/ /pubmed/36671607 http://dx.doi.org/10.3390/bioengineering10010035 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Tan, Yujing
Su, Jianhui
Fu, Minghui
Zhang, Hongmei
Zeng, Haiyan
Recent Advances in Phage-Based Therapeutics for Multi-Drug Resistant Acinetobacter baumannii
title Recent Advances in Phage-Based Therapeutics for Multi-Drug Resistant Acinetobacter baumannii
title_full Recent Advances in Phage-Based Therapeutics for Multi-Drug Resistant Acinetobacter baumannii
title_fullStr Recent Advances in Phage-Based Therapeutics for Multi-Drug Resistant Acinetobacter baumannii
title_full_unstemmed Recent Advances in Phage-Based Therapeutics for Multi-Drug Resistant Acinetobacter baumannii
title_short Recent Advances in Phage-Based Therapeutics for Multi-Drug Resistant Acinetobacter baumannii
title_sort recent advances in phage-based therapeutics for multi-drug resistant acinetobacter baumannii
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855029/
https://www.ncbi.nlm.nih.gov/pubmed/36671607
http://dx.doi.org/10.3390/bioengineering10010035
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