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Prevalence, Clinico-Bacteriological Profile, and Antibiotic Resistance of Symptomatic Urinary Tract Infections in Pregnant Women

Background: Urinary tract infection (UTI) is a common complication in pregnancy. The prevalence varies between countries. This research aims at estimating the prevalence, clinico-bacteriological profile, antibiotic resistance, and risk factor analysis of symptomatic UTI in pregnancy. Method: This is...

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Autores principales: Dube, Rajani, Al-Zuheiri, Shatha Taher Salman, Syed, Mariyam, Harilal, Lekshmi, Zuhaira, Dean Allah Layth, Kar, Subhranshu Sekhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855124/
https://www.ncbi.nlm.nih.gov/pubmed/36671233
http://dx.doi.org/10.3390/antibiotics12010033
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author Dube, Rajani
Al-Zuheiri, Shatha Taher Salman
Syed, Mariyam
Harilal, Lekshmi
Zuhaira, Dean Allah Layth
Kar, Subhranshu Sekhar
author_facet Dube, Rajani
Al-Zuheiri, Shatha Taher Salman
Syed, Mariyam
Harilal, Lekshmi
Zuhaira, Dean Allah Layth
Kar, Subhranshu Sekhar
author_sort Dube, Rajani
collection PubMed
description Background: Urinary tract infection (UTI) is a common complication in pregnancy. The prevalence varies between countries. This research aims at estimating the prevalence, clinico-bacteriological profile, antibiotic resistance, and risk factor analysis of symptomatic UTI in pregnancy. Method: This is a prospective observational study conducted at the Abdullah Bin Omran Hospital, RAK, UAE, from March 2019 to February 2020. All pregnant women attending the antenatal clinic during this period were given a pre-validated questionnaire for the symptoms of UTI. In symptomatic patients, urine was sent for microscopy, culture, and sensitivity. Women were treated for UTI and were followed up for the rest of the pregnancy. Data analysis was performed by SPSS software version 24 using descriptive statistics and comparisons with significance at a p-value of <0.05. Results: The prevalence of symptomatic UTI was 17.9%. E.coli was the commonest isolate followed by Group B streptococcus. The commonest symptom reported was loin pain and the most common risk factor was diabetes. Women with risk factors are significantly more likely to have culture-positive UTIs. Most of the pathogens were sensitive to cefuroxime and benzyl penicillin. Risk of preterm labor was higher. Conclusions: Regular antenatal care and routine urine testing in all visits are recommended for early detection and treatment of UTI.
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spelling pubmed-98551242023-01-21 Prevalence, Clinico-Bacteriological Profile, and Antibiotic Resistance of Symptomatic Urinary Tract Infections in Pregnant Women Dube, Rajani Al-Zuheiri, Shatha Taher Salman Syed, Mariyam Harilal, Lekshmi Zuhaira, Dean Allah Layth Kar, Subhranshu Sekhar Antibiotics (Basel) Article Background: Urinary tract infection (UTI) is a common complication in pregnancy. The prevalence varies between countries. This research aims at estimating the prevalence, clinico-bacteriological profile, antibiotic resistance, and risk factor analysis of symptomatic UTI in pregnancy. Method: This is a prospective observational study conducted at the Abdullah Bin Omran Hospital, RAK, UAE, from March 2019 to February 2020. All pregnant women attending the antenatal clinic during this period were given a pre-validated questionnaire for the symptoms of UTI. In symptomatic patients, urine was sent for microscopy, culture, and sensitivity. Women were treated for UTI and were followed up for the rest of the pregnancy. Data analysis was performed by SPSS software version 24 using descriptive statistics and comparisons with significance at a p-value of <0.05. Results: The prevalence of symptomatic UTI was 17.9%. E.coli was the commonest isolate followed by Group B streptococcus. The commonest symptom reported was loin pain and the most common risk factor was diabetes. Women with risk factors are significantly more likely to have culture-positive UTIs. Most of the pathogens were sensitive to cefuroxime and benzyl penicillin. Risk of preterm labor was higher. Conclusions: Regular antenatal care and routine urine testing in all visits are recommended for early detection and treatment of UTI. MDPI 2022-12-25 /pmc/articles/PMC9855124/ /pubmed/36671233 http://dx.doi.org/10.3390/antibiotics12010033 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Dube, Rajani
Al-Zuheiri, Shatha Taher Salman
Syed, Mariyam
Harilal, Lekshmi
Zuhaira, Dean Allah Layth
Kar, Subhranshu Sekhar
Prevalence, Clinico-Bacteriological Profile, and Antibiotic Resistance of Symptomatic Urinary Tract Infections in Pregnant Women
title Prevalence, Clinico-Bacteriological Profile, and Antibiotic Resistance of Symptomatic Urinary Tract Infections in Pregnant Women
title_full Prevalence, Clinico-Bacteriological Profile, and Antibiotic Resistance of Symptomatic Urinary Tract Infections in Pregnant Women
title_fullStr Prevalence, Clinico-Bacteriological Profile, and Antibiotic Resistance of Symptomatic Urinary Tract Infections in Pregnant Women
title_full_unstemmed Prevalence, Clinico-Bacteriological Profile, and Antibiotic Resistance of Symptomatic Urinary Tract Infections in Pregnant Women
title_short Prevalence, Clinico-Bacteriological Profile, and Antibiotic Resistance of Symptomatic Urinary Tract Infections in Pregnant Women
title_sort prevalence, clinico-bacteriological profile, and antibiotic resistance of symptomatic urinary tract infections in pregnant women
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855124/
https://www.ncbi.nlm.nih.gov/pubmed/36671233
http://dx.doi.org/10.3390/antibiotics12010033
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