Cargando…

Fracture Healing in Elderly Mice and the Effect of an Additional Severe Blood Loss: A Radiographic and Biomechanical Murine Study

Femoral fractures and severe bleeding frequently occur in old patients showing a delayed healing. As there are no studies investigating the combined effect of high age and severe blood loss on fracture healing, this was examined radiographically and biomechanically in this study. Therefore, young an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bundkirchen, Katrin, Ye, Weikang, Nowak, Aleksander J., Lienenklaus, Stefan, Welke, Bastian, Relja, Borna, Neunaber, Claudia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855159/ https://www.ncbi.nlm.nih.gov/pubmed/36671642 http://dx.doi.org/10.3390/bioengineering10010070

Ejemplares similares

Traumatic injury pattern is of equal relevance as injury severity for experimental (poly)trauma modeling
por: Yang, Bing, et al.
Publicado: (2019)

Different experimental multiple trauma models induce comparable inflammation and organ injury
por: Relja, Borna, et al.
Publicado: (2020)

Impact of age on liver damage, inflammation, and molecular signaling pathways in response to femoral fracture and hemorrhage
por: Meng, Fanshuai, et al.
Publicado: (2023)

Acute Intoxication With Alcohol Reduces Trauma-Induced Proinflammatory Response and Barrier Breakdown in the Lung via the Wnt/β-Catenin Signaling Pathway
por: Noack, Laurens, et al.
Publicado: (2022)

Selective Inhibition of IL-6 Trans-Signaling Has No Beneficial Effect on the Posttraumatic Cytokine Release after Multiple Trauma in Mice
por: Homeier, Jil-Madeline, et al.
Publicado: (2021)

Reduced phagocytosis, ROS production and enhanced apoptosis of leukocytes upon alcohol drinking in healthy volunteers
por: Haag, Florian, et al.
Publicado: (2021)

Acute alcohol consumption increases systemic endotoxin bioactivity for days in healthy volunteers—with reduced intestinal barrier loss in female
por: Sturm, Ramona, et al.
Publicado: (2021)

Characteristics of Mesenchymal Stem Cells Are Independent of Bone Marrow Storage Temperatures
por: Schrodi, Valentin, et al.
Publicado: (2021)

Biomechanical and histological analyses of the fracture healing process after direct or prolonged reduction
por: Peterburs, Benedikt, et al.
Publicado: (2018)

Are the Properties of Bone Marrow-Derived Mesenchymal Stem Cells Influenced by Overweight and Obesity?
por: Zong, Qiang, et al.
Publicado: (2023)

The Impact of Acute or Chronic Alcohol Intake on the NF-κB Signaling Pathway in Alcohol-Related Liver Disease
por: Nowak, Aleksander J., et al.
Publicado: (2020)

Radiographic, Biomechanical and Histological Characterization of Femoral Fracture Healing in Aged CD-1 Mice
por: Menger, Maximilian M., et al.
Publicado: (2023)

Cytological Effects of Serum Isolated from Polytraumatized Patients on Human Bone Marrow-Derived Mesenchymal Stem Cells
por: Long, Yazhou, et al.
Publicado: (2021)

Acute Alcohol Intoxication Modulates Monocyte Subsets and Their Functions in a Time-Dependent Manner in Healthy Volunteers
por: Janicova, Andrea, et al.
Publicado: (2021)

Biomechanical Assessment of Three Osteosynthesis Constructs by Periprosthetic Humerus Fractures
por: Harb, Afif, et al.
Publicado: (2020)

Traumatic brain injury and bone healing: radiographic and biomechanical analyses of bone formation and stability in a combined murine trauma model
por: Locher, R.J., et al.
Publicado: (2015)

Effects of immune cells on mesenchymal stem cells during fracture healing
por: Ehnert, Sabrina, et al.
Publicado: (2021)

Suppression of the interleukin-1β-induced inflammatory response of human Chang liver cells by acute and subacute exposure to alcohol: an in vitro study
por: Mörs, Katharina, et al.
Publicado: (2018)

Characterization of Human, Ovine and Porcine Mesenchymal Stem Cells from Bone Marrow: Critical In Vitro Comparison with Regard to Humans
por: Westerkowsky, Elisa Katja, et al.
Publicado: (2023)

Radiographic features of teriparatide-induced healing of femoral fractures
por: Kim, Youngwoo, et al.
Publicado: (2015)

Structural and biomechanical responses of osseous healing: a novel murine nonunion model
por: Chaubey, Aditya, et al.
Publicado: (2013)

Histopathologic and Radiographic evaluation of the electroacupuncture effects on ulna fracture healing in dogs
por: Naddaf, H., et al.
Publicado: (2014)

Club Cell Protein 16 Attenuates CD16(bright)CD62(dim) Immunosuppressive Neutrophils in Damaged Tissue upon Posttraumatic Sepsis-Induced Lung Injury
por: Becker, Nils, et al.
Publicado: (2021)

Heterogeneity of murine periosteum progenitors involved in fracture healing
por: Matthews, Brya G, et al.
Publicado: (2021)

Preoperative chest radiographs in hip fracture patients: is there any additional value?
por: Loggers, Sverre A. I., et al.
Publicado: (2017)

Validation of the modified radiographic union score for tibia fractures (mRUST) in murine femoral fractures
por: Alentado, Vincent J., et al.
Publicado: (2022)

Biomechanical Characteristics of Osteoporotic Fracture Healing in Ovariectomized Rats: A Systematic Review
por: Chen, Lin, et al.
Publicado: (2016)

Glucocorticoid-induced delayed fracture healing and impaired bone biomechanical properties in mice
por: Liu, Yan-zhi, et al.
Publicado: (2018)

Biophysical Stimulation in Delayed Fracture Healing of Hand Phalanx: A Radiographic Evaluation
por: De Francesco, Francesco, et al.
Publicado: (2022)

Healing after Trauma—New Knowledge and Procedures for the Benefit of Our Patients
por: Neunaber, Claudia, et al.
Publicado: (2022)

Ethyl Pyruvate Reduces Systemic Leukocyte Activation via Caspase-1 and NF-κB After Blunt Chest Trauma and Haemorrhagic Shock
por: Dieteren, Scott, et al.
Publicado: (2020)

Fracture biomechanics influence local and systemic immune responses in a murine fracture-related infection model
por: Sabaté-Brescó, Marina, et al.
Publicado: (2021)

Biomechanical, histologic, and molecular characteristics of graft-tunnel healing in a murine modified ACL reconstruction model
por: Yu, Huan, et al.
Publicado: (2020)

Local Infiltrative Analgesia of Murine Femur Fractures In Vivo Does Not Inhibit Fracture Healing
por: Tyler, Andrew F, et al.
Publicado: (2022)

Influence of the Peripheral Nervous System on Murine Osteoporotic Fracture Healing and Fracture-Induced Hyperalgesia
por: Wank, Isabel, et al.
Publicado: (2022)

Morphological and biomechanical effects of vitamin K2 on fracture healing: An animal study on the rat tibia fracture model
por: Kays Ünal, Ömer, et al.
Publicado: (2023)

Damage-associated molecular patterns in trauma
por: Relja, Borna, et al.
Publicado: (2019)

M1 But Not M0 Extracellular Vesicles Induce Polarization of RAW264.7 Macrophages Via the TLR4-NFκB Pathway In Vitro
por: Shi, Yulong, et al.
Publicado: (2020)

Ethanol Intoxication Alleviates the Inflammatory Response of Remote Organs to Experimental Traumatic Brain Injury
por: Xu, Baolin, et al.
Publicado: (2020)

I-FABP as a Potential Marker for Intestinal Barrier Loss in Porcine Polytrauma
por: Vollrath, Jan Tilmann, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_v12ropahsaj37mvgrf9k9oh5lv