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Effects of Glyceryl Monolaurate on Production Performance, Egg Quality, Oviduct Cytokines and Intestinal Microflora of 66 Weeks Old Laying Hens

SIMPLE SUMMARY: It has been proved that glyceryl monolaurate is a safe and green additive in food and feed. The purpose of this experiment was to study the potential application value of glyceryl monolaurate in the diet of laying hens in the late laying period. Our results indicate that the dietary...

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Autores principales: Cui, Zhenchuan, Zhang, Ruiqiang, Dai, Bing, Fu, Chunsheng, Zhao, Guiling, Xu, Yinglei, Yang, Caimei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855180/
https://www.ncbi.nlm.nih.gov/pubmed/36670755
http://dx.doi.org/10.3390/ani13020215
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author Cui, Zhenchuan
Zhang, Ruiqiang
Dai, Bing
Fu, Chunsheng
Zhao, Guiling
Xu, Yinglei
Yang, Caimei
author_facet Cui, Zhenchuan
Zhang, Ruiqiang
Dai, Bing
Fu, Chunsheng
Zhao, Guiling
Xu, Yinglei
Yang, Caimei
author_sort Cui, Zhenchuan
collection PubMed
description SIMPLE SUMMARY: It has been proved that glyceryl monolaurate is a safe and green additive in food and feed. The purpose of this experiment was to study the potential application value of glyceryl monolaurate in the diet of laying hens in the late laying period. Our results indicate that the dietary supplementation of glyceryl monolaurate could significantly improve laying performance and egg quality, reducing inflammation, promoting immune function and intestinal barrier function as well as regulating the intestinal flora of laying hens. ABSTRACT: The principal purpose of this research was to study the effects of glycerol monolaurate (GML) on the production performance; egg quality; health state of the oviduct, ovary and ileum; and gut microbiota of laying hens in the later stage. The laying hens were randomly assigned to two groups: a control group and an experiment group, for which 1000 mg/kg of GML was added to a control diet. The results showed that GML increased the laying rate, average egg weight, albumen height, yolk color and Haugh unit and decreased the feed conversion ratio and defective eggs (p < 0.05). GML increased the intestinal villi height and the ratio of villus height to crypt depth (p < 0.05). Moreover, GML improved the contents of cytokines in the oviduct, ovary and ileum mucosa; ameliorated the expression of TLR2, TLR4, MyD88, IL-4, IL-1β and TNF-α; and increased the expression of Occludin and Muc-2 in the ileal mucosa. The supplementation of GML increased the volatile fatty acids in the cecal contents, such as acetic acid and propionic acid, and up-regulated Bacteroides (p < 0.01) and Alistipes (p < 0.05) richness in the cecal contents. In summary, GML improved production performance, egg quality and immunity; ameliorated the health status of the oviduct, ovary and ileum; enhanced the intestinal barrier function; improved the content of intestinal volatile fatty acids; and regulated the abundance of cecal flora.
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spelling pubmed-98551802023-01-21 Effects of Glyceryl Monolaurate on Production Performance, Egg Quality, Oviduct Cytokines and Intestinal Microflora of 66 Weeks Old Laying Hens Cui, Zhenchuan Zhang, Ruiqiang Dai, Bing Fu, Chunsheng Zhao, Guiling Xu, Yinglei Yang, Caimei Animals (Basel) Article SIMPLE SUMMARY: It has been proved that glyceryl monolaurate is a safe and green additive in food and feed. The purpose of this experiment was to study the potential application value of glyceryl monolaurate in the diet of laying hens in the late laying period. Our results indicate that the dietary supplementation of glyceryl monolaurate could significantly improve laying performance and egg quality, reducing inflammation, promoting immune function and intestinal barrier function as well as regulating the intestinal flora of laying hens. ABSTRACT: The principal purpose of this research was to study the effects of glycerol monolaurate (GML) on the production performance; egg quality; health state of the oviduct, ovary and ileum; and gut microbiota of laying hens in the later stage. The laying hens were randomly assigned to two groups: a control group and an experiment group, for which 1000 mg/kg of GML was added to a control diet. The results showed that GML increased the laying rate, average egg weight, albumen height, yolk color and Haugh unit and decreased the feed conversion ratio and defective eggs (p < 0.05). GML increased the intestinal villi height and the ratio of villus height to crypt depth (p < 0.05). Moreover, GML improved the contents of cytokines in the oviduct, ovary and ileum mucosa; ameliorated the expression of TLR2, TLR4, MyD88, IL-4, IL-1β and TNF-α; and increased the expression of Occludin and Muc-2 in the ileal mucosa. The supplementation of GML increased the volatile fatty acids in the cecal contents, such as acetic acid and propionic acid, and up-regulated Bacteroides (p < 0.01) and Alistipes (p < 0.05) richness in the cecal contents. In summary, GML improved production performance, egg quality and immunity; ameliorated the health status of the oviduct, ovary and ileum; enhanced the intestinal barrier function; improved the content of intestinal volatile fatty acids; and regulated the abundance of cecal flora. MDPI 2023-01-06 /pmc/articles/PMC9855180/ /pubmed/36670755 http://dx.doi.org/10.3390/ani13020215 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Cui, Zhenchuan
Zhang, Ruiqiang
Dai, Bing
Fu, Chunsheng
Zhao, Guiling
Xu, Yinglei
Yang, Caimei
Effects of Glyceryl Monolaurate on Production Performance, Egg Quality, Oviduct Cytokines and Intestinal Microflora of 66 Weeks Old Laying Hens
title Effects of Glyceryl Monolaurate on Production Performance, Egg Quality, Oviduct Cytokines and Intestinal Microflora of 66 Weeks Old Laying Hens
title_full Effects of Glyceryl Monolaurate on Production Performance, Egg Quality, Oviduct Cytokines and Intestinal Microflora of 66 Weeks Old Laying Hens
title_fullStr Effects of Glyceryl Monolaurate on Production Performance, Egg Quality, Oviduct Cytokines and Intestinal Microflora of 66 Weeks Old Laying Hens
title_full_unstemmed Effects of Glyceryl Monolaurate on Production Performance, Egg Quality, Oviduct Cytokines and Intestinal Microflora of 66 Weeks Old Laying Hens
title_short Effects of Glyceryl Monolaurate on Production Performance, Egg Quality, Oviduct Cytokines and Intestinal Microflora of 66 Weeks Old Laying Hens
title_sort effects of glyceryl monolaurate on production performance, egg quality, oviduct cytokines and intestinal microflora of 66 weeks old laying hens
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855180/
https://www.ncbi.nlm.nih.gov/pubmed/36670755
http://dx.doi.org/10.3390/ani13020215
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