Cargando…

Plateletpheresis donor deferral pattern: A retrospective 4-year data analysis at tertiary care center in India

BACKGROUND: Increasing demand of single donor platelet requires blood banks to expand the donor pool. A reassessment of donor deferral criteria for plateletpheresis is required to ensure that this increasing demand is met without compromising on product quality and donor safety. AIMS: (1) To list th...

Descripción completa

Detalles Bibliográficos
Autores principales: Yadav, Brijesh Kumar, Shrivastava, Harsha, Katharia, Rahul, Chaudhary, Rajendra K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855204/
https://www.ncbi.nlm.nih.gov/pubmed/36687534
http://dx.doi.org/10.4103/ajts.ajts_96_22
_version_ 1784873322647912448
author Yadav, Brijesh Kumar
Shrivastava, Harsha
Katharia, Rahul
Chaudhary, Rajendra K.
author_facet Yadav, Brijesh Kumar
Shrivastava, Harsha
Katharia, Rahul
Chaudhary, Rajendra K.
author_sort Yadav, Brijesh Kumar
collection PubMed
description BACKGROUND: Increasing demand of single donor platelet requires blood banks to expand the donor pool. A reassessment of donor deferral criteria for plateletpheresis is required to ensure that this increasing demand is met without compromising on product quality and donor safety. AIMS: (1) To list the various causes of SDP donor deferral. (2) To discuss various approaches to minimize it. MATERIALS AND METHODS: Data of plateletpheresis donor deferral were collected from records retrospectively over a period of 4 years from January 2017 to December 2020. STATISTICAL ANALYSIS: All statistical tests were performed using IBM SPSS software for Windows version 20. Categorical variables were presented as proportions, while continuous variables were presented as mean with standard deviation, mean calculated P < 0.05 was considered statistically significant. RESULTS: Out of the 7478 donors screened for plateletpheresis procedure, 3232 (43.2%) were deferred among which 3089 (42.5%) were male and 142 (63.1%) were female donors. Majority (96.5%) of deferral were temporary. These included low platelet count (47.4%) followed by poor venous access (22.4%) and low hemoglobin (Hb) (7.2%). Among the donors deferred for low Hb, 24.7% (58 out of 234) had Hb between 12 and 12.4 g%. Similarly, among donor deferred for low platelet count, 12% (184 out of 1532) had platelet count between 140 and 149 × 10(3)/μl. CONCLUSION: There is potential for increasing the number of eligible plateletpheresis donors if the present donor selection criteria were relaxed to a minimum Hb of 12 g/dl and minimum platelet count of 140 × 10(3)/μl.
format Online
Article
Text
id pubmed-9855204
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Wolters Kluwer - Medknow
record_format MEDLINE/PubMed
spelling pubmed-98552042023-01-21 Plateletpheresis donor deferral pattern: A retrospective 4-year data analysis at tertiary care center in India Yadav, Brijesh Kumar Shrivastava, Harsha Katharia, Rahul Chaudhary, Rajendra K. Asian J Transfus Sci Original Article BACKGROUND: Increasing demand of single donor platelet requires blood banks to expand the donor pool. A reassessment of donor deferral criteria for plateletpheresis is required to ensure that this increasing demand is met without compromising on product quality and donor safety. AIMS: (1) To list the various causes of SDP donor deferral. (2) To discuss various approaches to minimize it. MATERIALS AND METHODS: Data of plateletpheresis donor deferral were collected from records retrospectively over a period of 4 years from January 2017 to December 2020. STATISTICAL ANALYSIS: All statistical tests were performed using IBM SPSS software for Windows version 20. Categorical variables were presented as proportions, while continuous variables were presented as mean with standard deviation, mean calculated P < 0.05 was considered statistically significant. RESULTS: Out of the 7478 donors screened for plateletpheresis procedure, 3232 (43.2%) were deferred among which 3089 (42.5%) were male and 142 (63.1%) were female donors. Majority (96.5%) of deferral were temporary. These included low platelet count (47.4%) followed by poor venous access (22.4%) and low hemoglobin (Hb) (7.2%). Among the donors deferred for low Hb, 24.7% (58 out of 234) had Hb between 12 and 12.4 g%. Similarly, among donor deferred for low platelet count, 12% (184 out of 1532) had platelet count between 140 and 149 × 10(3)/μl. CONCLUSION: There is potential for increasing the number of eligible plateletpheresis donors if the present donor selection criteria were relaxed to a minimum Hb of 12 g/dl and minimum platelet count of 140 × 10(3)/μl. Wolters Kluwer - Medknow 2022 2022-11-12 /pmc/articles/PMC9855204/ /pubmed/36687534 http://dx.doi.org/10.4103/ajts.ajts_96_22 Text en Copyright: © 2022 Asian Journal of Transfusion Science https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Yadav, Brijesh Kumar
Shrivastava, Harsha
Katharia, Rahul
Chaudhary, Rajendra K.
Plateletpheresis donor deferral pattern: A retrospective 4-year data analysis at tertiary care center in India
title Plateletpheresis donor deferral pattern: A retrospective 4-year data analysis at tertiary care center in India
title_full Plateletpheresis donor deferral pattern: A retrospective 4-year data analysis at tertiary care center in India
title_fullStr Plateletpheresis donor deferral pattern: A retrospective 4-year data analysis at tertiary care center in India
title_full_unstemmed Plateletpheresis donor deferral pattern: A retrospective 4-year data analysis at tertiary care center in India
title_short Plateletpheresis donor deferral pattern: A retrospective 4-year data analysis at tertiary care center in India
title_sort plateletpheresis donor deferral pattern: a retrospective 4-year data analysis at tertiary care center in india
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855204/
https://www.ncbi.nlm.nih.gov/pubmed/36687534
http://dx.doi.org/10.4103/ajts.ajts_96_22
work_keys_str_mv AT yadavbrijeshkumar plateletpheresisdonordeferralpatternaretrospective4yeardataanalysisattertiarycarecenterinindia
AT shrivastavaharsha plateletpheresisdonordeferralpatternaretrospective4yeardataanalysisattertiarycarecenterinindia
AT kathariarahul plateletpheresisdonordeferralpatternaretrospective4yeardataanalysisattertiarycarecenterinindia
AT chaudharyrajendrak plateletpheresisdonordeferralpatternaretrospective4yeardataanalysisattertiarycarecenterinindia