A Curious Case of Suspicious Lymphadenopathy in a Hereditary Spherocytosis Patient Reported as Extramedullary Hematopoiesis

We present a case of a 23-year-old male patient with complaints of fever, cough, and persistent anemia for the past 6 months and with a known history of hereditary spherocytosis. Computed tomography (CT) thorax demonstrated multiple paravertebral lesions in the bilateral thoracic cavities, suggestiv...

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Autores principales: Khan, Dikhra, Sharma, Anshul, Sagar, Sambit, Thayumanavan, T., Kumar, Rakesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855240/
https://www.ncbi.nlm.nih.gov/pubmed/36686299
http://dx.doi.org/10.4103/ijnm.ijnm_10_22
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author Khan, Dikhra
Sharma, Anshul
Sagar, Sambit
Thayumanavan, T.
Kumar, Rakesh
author_facet Khan, Dikhra
Sharma, Anshul
Sagar, Sambit
Thayumanavan, T.
Kumar, Rakesh
author_sort Khan, Dikhra
collection PubMed
description We present a case of a 23-year-old male patient with complaints of fever, cough, and persistent anemia for the past 6 months and with a known history of hereditary spherocytosis. Computed tomography (CT) thorax demonstrated multiple paravertebral lesions in the bilateral thoracic cavities, suggestive of lymphadenopathy; subsequently, (18)Flurodeoxyglucose PET/CT was done with suspicion of lymphoma, which showed no significant metabolic activity in those lesions. Thus, in view of clinical and metabolic status, lesions were considered extramedullary hematopoiesis (EMH). This case highlights the importance of considering EMH, while interpreting suspicious lymphadenopathy in cases of chronic anemia and also possible scan findings in the same.
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spelling pubmed-98552402023-01-21 A Curious Case of Suspicious Lymphadenopathy in a Hereditary Spherocytosis Patient Reported as Extramedullary Hematopoiesis Khan, Dikhra Sharma, Anshul Sagar, Sambit Thayumanavan, T. Kumar, Rakesh Indian J Nucl Med Interesting Image We present a case of a 23-year-old male patient with complaints of fever, cough, and persistent anemia for the past 6 months and with a known history of hereditary spherocytosis. Computed tomography (CT) thorax demonstrated multiple paravertebral lesions in the bilateral thoracic cavities, suggestive of lymphadenopathy; subsequently, (18)Flurodeoxyglucose PET/CT was done with suspicion of lymphoma, which showed no significant metabolic activity in those lesions. Thus, in view of clinical and metabolic status, lesions were considered extramedullary hematopoiesis (EMH). This case highlights the importance of considering EMH, while interpreting suspicious lymphadenopathy in cases of chronic anemia and also possible scan findings in the same. Wolters Kluwer - Medknow 2022 2022-11-02 /pmc/articles/PMC9855240/ /pubmed/36686299 http://dx.doi.org/10.4103/ijnm.ijnm_10_22 Text en Copyright: © 2022 Indian Journal of Nuclear Medicine https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Interesting Image
Khan, Dikhra
Sharma, Anshul
Sagar, Sambit
Thayumanavan, T.
Kumar, Rakesh
A Curious Case of Suspicious Lymphadenopathy in a Hereditary Spherocytosis Patient Reported as Extramedullary Hematopoiesis
title A Curious Case of Suspicious Lymphadenopathy in a Hereditary Spherocytosis Patient Reported as Extramedullary Hematopoiesis
title_full A Curious Case of Suspicious Lymphadenopathy in a Hereditary Spherocytosis Patient Reported as Extramedullary Hematopoiesis
title_fullStr A Curious Case of Suspicious Lymphadenopathy in a Hereditary Spherocytosis Patient Reported as Extramedullary Hematopoiesis
title_full_unstemmed A Curious Case of Suspicious Lymphadenopathy in a Hereditary Spherocytosis Patient Reported as Extramedullary Hematopoiesis
title_short A Curious Case of Suspicious Lymphadenopathy in a Hereditary Spherocytosis Patient Reported as Extramedullary Hematopoiesis
title_sort curious case of suspicious lymphadenopathy in a hereditary spherocytosis patient reported as extramedullary hematopoiesis
topic Interesting Image
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855240/
https://www.ncbi.nlm.nih.gov/pubmed/36686299
http://dx.doi.org/10.4103/ijnm.ijnm_10_22
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