Ga-68 Chemokine Receptor-4 PET/CT Imaging in Schminke Type of Nasopharyngeal Carcinoma

Nasopharyngeal carcinoma is a rare malignancy of the head-and-neck region. It is associated with Epstein–Barr virus infection and smoking. Its association with breast cancer is also infrequent. Chemokine receptor (CXCR)-4 imaging is a newer agent for imaging many malignancies with a good diagnostic...

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Detalles Bibliográficos
Autores principales: Ramachandran, Arivan, Krishnaraju, Venkata Subramanian, Kumar, Rajender, Shukla, Jaya, Laroya, Ishita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855242/
https://www.ncbi.nlm.nih.gov/pubmed/36686303
http://dx.doi.org/10.4103/ijnm.ijnm_184_21
Descripción
Sumario:Nasopharyngeal carcinoma is a rare malignancy of the head-and-neck region. It is associated with Epstein–Barr virus infection and smoking. Its association with breast cancer is also infrequent. Chemokine receptor (CXCR)-4 imaging is a newer agent for imaging many malignancies with a good diagnostic value. We present a case of a young female diagnosed with left breast carcinoma in whom Ga-68 CXCR-4 PET/CT demonstrated tracer avid lesion in the nasopharynx. Biopsy of the nasopharyngeal lesion revealed Schminke type of lymphoepithelial cancer, indicating CXCR-4 PET/CT as a potential imaging modality for lymphoepithelial malignancy.

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