Ga-68 Chemokine Receptor-4 PET/CT Imaging in Schminke Type of Nasopharyngeal Carcinoma

Nasopharyngeal carcinoma is a rare malignancy of the head-and-neck region. It is associated with Epstein–Barr virus infection and smoking. Its association with breast cancer is also infrequent. Chemokine receptor (CXCR)-4 imaging is a newer agent for imaging many malignancies with a good diagnostic...

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Autores principales: Ramachandran, Arivan, Krishnaraju, Venkata Subramanian, Kumar, Rajender, Shukla, Jaya, Laroya, Ishita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Interesting Image
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855242/
https://www.ncbi.nlm.nih.gov/pubmed/36686303
http://dx.doi.org/10.4103/ijnm.ijnm_184_21
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author Ramachandran, Arivan
Krishnaraju, Venkata Subramanian
Kumar, Rajender
Shukla, Jaya
Laroya, Ishita
author_facet Ramachandran, Arivan
Krishnaraju, Venkata Subramanian
Kumar, Rajender
Shukla, Jaya
Laroya, Ishita
author_sort Ramachandran, Arivan
collection PubMed
description Nasopharyngeal carcinoma is a rare malignancy of the head-and-neck region. It is associated with Epstein–Barr virus infection and smoking. Its association with breast cancer is also infrequent. Chemokine receptor (CXCR)-4 imaging is a newer agent for imaging many malignancies with a good diagnostic value. We present a case of a young female diagnosed with left breast carcinoma in whom Ga-68 CXCR-4 PET/CT demonstrated tracer avid lesion in the nasopharynx. Biopsy of the nasopharyngeal lesion revealed Schminke type of lymphoepithelial cancer, indicating CXCR-4 PET/CT as a potential imaging modality for lymphoepithelial malignancy.
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spelling pubmed-98552422023-01-21 Ga-68 Chemokine Receptor-4 PET/CT Imaging in Schminke Type of Nasopharyngeal Carcinoma Ramachandran, Arivan Krishnaraju, Venkata Subramanian Kumar, Rajender Shukla, Jaya Laroya, Ishita Indian J Nucl Med Interesting Image Nasopharyngeal carcinoma is a rare malignancy of the head-and-neck region. It is associated with Epstein–Barr virus infection and smoking. Its association with breast cancer is also infrequent. Chemokine receptor (CXCR)-4 imaging is a newer agent for imaging many malignancies with a good diagnostic value. We present a case of a young female diagnosed with left breast carcinoma in whom Ga-68 CXCR-4 PET/CT demonstrated tracer avid lesion in the nasopharynx. Biopsy of the nasopharyngeal lesion revealed Schminke type of lymphoepithelial cancer, indicating CXCR-4 PET/CT as a potential imaging modality for lymphoepithelial malignancy. Wolters Kluwer - Medknow 2022 2022-11-02 /pmc/articles/PMC9855242/ /pubmed/36686303 http://dx.doi.org/10.4103/ijnm.ijnm_184_21 Text en Copyright: © 2022 Indian Journal of Nuclear Medicine https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Interesting Image
Ramachandran, Arivan
Krishnaraju, Venkata Subramanian
Kumar, Rajender
Shukla, Jaya
Laroya, Ishita
Ga-68 Chemokine Receptor-4 PET/CT Imaging in Schminke Type of Nasopharyngeal Carcinoma
title Ga-68 Chemokine Receptor-4 PET/CT Imaging in Schminke Type of Nasopharyngeal Carcinoma
title_full Ga-68 Chemokine Receptor-4 PET/CT Imaging in Schminke Type of Nasopharyngeal Carcinoma
title_fullStr Ga-68 Chemokine Receptor-4 PET/CT Imaging in Schminke Type of Nasopharyngeal Carcinoma
title_full_unstemmed Ga-68 Chemokine Receptor-4 PET/CT Imaging in Schminke Type of Nasopharyngeal Carcinoma
title_short Ga-68 Chemokine Receptor-4 PET/CT Imaging in Schminke Type of Nasopharyngeal Carcinoma
title_sort ga-68 chemokine receptor-4 pet/ct imaging in schminke type of nasopharyngeal carcinoma
topic Interesting Image
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855242/
https://www.ncbi.nlm.nih.gov/pubmed/36686303
http://dx.doi.org/10.4103/ijnm.ijnm_184_21
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AT kumarrajender ga68chemokinereceptor4petctimaginginschminketypeofnasopharyngealcarcinoma
AT shuklajaya ga68chemokinereceptor4petctimaginginschminketypeofnasopharyngealcarcinoma
AT laroyaishita ga68chemokinereceptor4petctimaginginschminketypeofnasopharyngealcarcinoma

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