(99m)Tc-Ethambutol Scan with SPECT/CT in Knee Joint Tuberculosis

Modalities for in vivo imaging of Mycobacterium tuberculosis are limited and inadequately studied. One such modality is (99m)Tc-ethambutol scintigraphy which has shown promising results for diagnosis of tuberculosis (TB). Ethambutol, one of the primary antitubercular drugs, is bacteriostatic which a...

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Autores principales: Kalra, Simran, Damle, Nishikant Avinash, Ranjan, Piyush, Sikdar, Sunit, Arora, Geetanjali, Goyal, Ankur, Gautam, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Interesting Image
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855250/
https://www.ncbi.nlm.nih.gov/pubmed/36686304
http://dx.doi.org/10.4103/ijnm.ijnm_16_22
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author Kalra, Simran
Damle, Nishikant Avinash
Ranjan, Piyush
Sikdar, Sunit
Arora, Geetanjali
Goyal, Ankur
Gautam, Deepak
author_facet Kalra, Simran
Damle, Nishikant Avinash
Ranjan, Piyush
Sikdar, Sunit
Arora, Geetanjali
Goyal, Ankur
Gautam, Deepak
author_sort Kalra, Simran
collection PubMed
description Modalities for in vivo imaging of Mycobacterium tuberculosis are limited and inadequately studied. One such modality is (99m)Tc-ethambutol scintigraphy which has shown promising results for diagnosis of tuberculosis (TB). Ethambutol, one of the primary antitubercular drugs, is bacteriostatic which acts on the mycolic acid cell wall synthesis of the M. tuberculosis. However, literature on its utility is scarce. The few studies that exist have reported its sensitivity and specificity between 90%– 95% and 71%–85%. We present here a case demonstrating the role of (99m)Tc-ethambutol scan in knee joint TB.
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spelling pubmed-98552502023-01-21 (99m)Tc-Ethambutol Scan with SPECT/CT in Knee Joint Tuberculosis Kalra, Simran Damle, Nishikant Avinash Ranjan, Piyush Sikdar, Sunit Arora, Geetanjali Goyal, Ankur Gautam, Deepak Indian J Nucl Med Interesting Image Modalities for in vivo imaging of Mycobacterium tuberculosis are limited and inadequately studied. One such modality is (99m)Tc-ethambutol scintigraphy which has shown promising results for diagnosis of tuberculosis (TB). Ethambutol, one of the primary antitubercular drugs, is bacteriostatic which acts on the mycolic acid cell wall synthesis of the M. tuberculosis. However, literature on its utility is scarce. The few studies that exist have reported its sensitivity and specificity between 90%– 95% and 71%–85%. We present here a case demonstrating the role of (99m)Tc-ethambutol scan in knee joint TB. Wolters Kluwer - Medknow 2022 2022-11-02 /pmc/articles/PMC9855250/ /pubmed/36686304 http://dx.doi.org/10.4103/ijnm.ijnm_16_22 Text en Copyright: © 2022 Indian Journal of Nuclear Medicine https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Interesting Image
Kalra, Simran
Damle, Nishikant Avinash
Ranjan, Piyush
Sikdar, Sunit
Arora, Geetanjali
Goyal, Ankur
Gautam, Deepak
(99m)Tc-Ethambutol Scan with SPECT/CT in Knee Joint Tuberculosis
title (99m)Tc-Ethambutol Scan with SPECT/CT in Knee Joint Tuberculosis
title_full (99m)Tc-Ethambutol Scan with SPECT/CT in Knee Joint Tuberculosis
title_fullStr (99m)Tc-Ethambutol Scan with SPECT/CT in Knee Joint Tuberculosis
title_full_unstemmed (99m)Tc-Ethambutol Scan with SPECT/CT in Knee Joint Tuberculosis
title_short (99m)Tc-Ethambutol Scan with SPECT/CT in Knee Joint Tuberculosis
title_sort (99m)tc-ethambutol scan with spect/ct in knee joint tuberculosis
topic Interesting Image
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855250/
https://www.ncbi.nlm.nih.gov/pubmed/36686304
http://dx.doi.org/10.4103/ijnm.ijnm_16_22
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