1-(Arylsulfonyl-isoindol-2-yl)piperazines as 5-HT(6)R Antagonists: Mechanochemical Synthesis, In Vitro Pharmacological Properties and Glioprotective Activity

In addition to the canonical Gs adenylyl cyclase pathway, the serotonin type 6 receptor (5-HT(6)R) recruits additional signaling pathways that control cognitive function, brain development, and synaptic plasticity in an agonist-dependent and independent manner. Considering that aberrant constitutive...

Descripción completa

Detalles Bibliográficos
Autores principales: Canale, Vittorio, Trybała, Wojciech, Chaumont-Dubel, Séverine, Koczurkiewicz-Adamczyk, Paulina, Satała, Grzegorz, Bento, Ophélie, Blicharz-Futera, Klaudia, Bantreil, Xavier, Pękala, Elżbieta, Bojarski, Andrzej J., Lamaty, Frédéric, Marin, Philippe, Zajdel, Paweł
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855333/
https://www.ncbi.nlm.nih.gov/pubmed/36671397
http://dx.doi.org/10.3390/biom13010012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855333/
https://www.ncbi.nlm.nih.gov/pubmed/36671397
http://dx.doi.org/10.3390/biom13010012

Ejemplares similares