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Andrographis Reverses Gemcitabine Resistance through Regulation of ERBB3 and Calcium Signaling Pathway in Pancreatic Ductal Adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies, primarily due to intrinsic or acquired resistance to chemotherapy, such as Gemcitabine (Gem). Naturally occurring botanicals, including Andrographis (Andro), can help enhance the anti-tumorigenic therapeutic efficacy of...

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Detalles Bibliográficos
Autores principales: Okuno, Keisuke, Xu, Caiming, Pascual-Sabater, Silvia, Tokunaga, Masanori, Takayama, Tetsuji, Han, Haiyong, Fillat, Cristina, Kinugasa, Yusuke, Goel, Ajay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855441/
https://www.ncbi.nlm.nih.gov/pubmed/36672630
http://dx.doi.org/10.3390/biomedicines11010119