Cargando…

Andrographis Reverses Gemcitabine Resistance through Regulation of ERBB3 and Calcium Signaling Pathway in Pancreatic Ductal Adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies, primarily due to intrinsic or acquired resistance to chemotherapy, such as Gemcitabine (Gem). Naturally occurring botanicals, including Andrographis (Andro), can help enhance the anti-tumorigenic therapeutic efficacy of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Okuno, Keisuke, Xu, Caiming, Pascual-Sabater, Silvia, Tokunaga, Masanori, Takayama, Tetsuji, Han, Haiyong, Fillat, Cristina, Kinugasa, Yusuke, Goel, Ajay
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855441/ https://www.ncbi.nlm.nih.gov/pubmed/36672630 http://dx.doi.org/10.3390/biomedicines11010119

Ejemplares similares

Berberine Overcomes Gemcitabine-Associated Chemoresistance through Regulation of Rap1/PI3K-Akt Signaling in Pancreatic Ductal Adenocarcinoma
por: Okuno, Keisuke, et al.
Publicado: (2022)

Berberine and Oligomeric Proanthocyanidins Exhibit Synergistic Efficacy Through Regulation of PI3K-Akt Signaling Pathway in Colorectal Cancer
por: Okuno, Keisuke, et al.
Publicado: (2022)

Corrigendum: Berberine and Oligomeric Proanthocyanidins Exhibit Synergistic Efficacy Through Regulation of PI3K-Akt Signaling Pathway in Colorectal Cancer
por: Okuno, Keisuke, et al.
Publicado: (2022)

Curcumin and Andrographis Exhibit Anti-Tumor Effects in Colorectal Cancer via Activation of Ferroptosis and Dual Suppression of Glutathione Peroxidase-4 and Ferroptosis Suppressor Protein-1
por: Miyazaki, Katsuki, et al.
Publicado: (2023)

A microRNA signature for risk-stratification and response prediction to FOLFOX-based adjuvant therapy in stage II and III colorectal cancer
por: Okuno, Keisuke, et al.
Publicado: (2023)

Prognostic Value of Intraoperative Blood Transfusion in Patients with Adenocarcinoma of the Esophagogastric Junction
por: Nakajima, Kei, et al.
Publicado: (2022)

Minimally Invasive Surgery for Colorectal Cancer
por: Yamauchi, Shinichi, et al.
Publicado: (2021)

In vitro anti-inflammatory and wound healing properties of Andrographis echioides and Andrographis paniculata
por: Selvaraj, Kaviya, et al.
Publicado: (2022)

Differential impact of the ERBB receptors EGFR and ERBB2 on the initiation of precursor lesions of pancreatic ductal adenocarcinoma
por: Meyers, Nora, et al.
Publicado: (2020)

A Combined Treatment with Berberine and Andrographis Exhibits Enhanced Anti-Cancer Activity through Suppression of DNA Replication in Colorectal Cancer
por: Zhao, Yinghui, et al.
Publicado: (2022)

Enhanced anti-cancer activity of andrographis with oligomeric proanthocyanidins through activation of metabolic and ferroptosis pathways in colorectal cancer
por: Shimura, Tadanobu, et al.
Publicado: (2021)

An exosome-based liquid biopsy signature for pre-operative identification of lymph node metastasis in patients with pathological high-risk T1 colorectal cancer
por: Miyazaki, Katsuki, et al.
Publicado: (2023)

In vitro antioxidant and anti-diabetic analysis of Andrographis echioides and Andrographis paniculata ethanol extract
por: Shreya Reddy, Chevuru Sai, et al.
Publicado: (2022)

ErbB3 is required for ductal morphogenesis in the mouse mammary gland
por: Jackson-Fisher, Amy J, et al.
Publicado: (2008)

Induction Chemotherapy With FOLFIRINOX Followed by Chemoradiation With Gemcitabine in Patients With Borderline-Resectable Pancreatic Ductal Adenocarcinoma
por: Acuna-Villaorduna, Ana, et al.
Publicado: (2022)

Real-world outcomes of adjuvant gemcitabine versus gemcitabine plus capecitabine for resected pancreatic ductal adenocarcinoma
por: Kang, Sora, et al.
Publicado: (2022)

Real‐world evidence of adjuvant gemcitabine plus capecitabine vs gemcitabine monotherapy for pancreatic ductal adenocarcinoma
por: de Jong, Evelien J. M., et al.
Publicado: (2021)

Is Andrographis paniculata extract and andrographolide anaphylactic?
por: Richard, Edwin Jothie, et al.
Publicado: (2017)

Robotic-assisted Surgery: Expanding Indication to Colon Cancer in Japan
por: Yamauchi, Shinichi, et al.
Publicado: (2022)

A comparative assessment of in vitro cytotoxic activity and phytochemical profiling of Andrographis nallamalayana J.L.Ellis and Andrographis paniculata (Burm. f.) Nees using UPLC-QTOF-MS/MS approach
por: Goel, Narender, et al.
Publicado: (2021)

Randomized Phase II Study of First‐Line Biweekly Gemcitabine and Carboplatin Versus Biweekly Gemcitabine and Carboplatin plus Maintenance Gemcitabine in Elderly Patients with Untreated Non‐Small Cell Lung Cancer: LOGIK0801
por: Takayama, Koichi, et al.
Publicado: (2020)

Calcium channel blockers potentiate gemcitabine chemotherapy in pancreatic cancer
por: Principe, Daniel R., et al.
Publicado: (2022)

Integrated stress response is critical for gemcitabine resistance in pancreatic ductal adenocarcinoma
por: Palam, L R, et al.
Publicado: (2015)

Circular RNA Signature Predicts Gemcitabine Resistance of Pancreatic Ductal Adenocarcinoma
por: Shao, Feng, et al.
Publicado: (2018)

Resistance to Gemcitabine in Pancreatic Ductal Adenocarcinoma: A Physiopathologic and Pharmacologic Review
por: Koltai, Tomas, et al.
Publicado: (2022)

Anti-tumor effect of avadomide in gemcitabine-resistant pancreatic ductal adenocarcinoma
por: Nishi, Hidemi, et al.
Publicado: (2023)

Antibacterial Activity of Ethanol Extract of Andrographis paniculata
por: Mishra, U. S., et al.
Publicado: (2009)

PHYTOCHEMICAL OBSERVATIONS ON SOME SPECIES OF ANDROGRAPHIS WALL
por: Alagesaboopathi, C., et al.
Publicado: (1996)

ANTIVENOM ACTIVITIES OF SOME SPECIES OF ANDROGRAPHIS WALL
por: Balu, S., et al.
Publicado: (1995)

NOMENCLATURAL CONFUSION OF SOME SPECIES OF ANDROGRAPHIS WALL
por: Balu, S., et al.
Publicado: (1995)

PROPAGATION OF ANDROGRAPHIS LINEATA NEES BY STEM CUTTINGS
por: Balu, S., et al.
Publicado: (1995)

ANTIPYRETIC ACTIVITIES OF SOME SPECIES OF ANDROGRAPHIS WALL
por: Balu, S., et al.
Publicado: (1993)

Chromosome Level Genome Assembly of Andrographis paniculata
por: Liang, Ying, et al.
Publicado: (2020)

Targeting ErbB3-mediated stromal–epithelial interactions in pancreatic ductal adenocarcinoma
por: Liles, J S, et al.
Publicado: (2011)

Unraveling ERBB network dynamics upon betacellulin signaling in pancreatic ductal adenocarcinoma in mice
por: Hedegger, Kathrin, et al.
Publicado: (2020)

Efficacy and safety of gemcitabine plus S-1 vs. gemcitabine plus nab-paclitaxel in treatment-naïve advanced pancreatic ductal adenocarcinoma
por: Zhu, Zhou, et al.
Publicado: (2023)

Correction to: Perioperative chemotherapy for locally advanced gastric cancer in Japan: current and future perspectives
por: Tokunaga, Masanori, et al.
Publicado: (2020)

Perioperative chemotherapy for locally advanced gastric cancer in Japan: current and future perspectives
por: Tokunaga, Masanori, et al.
Publicado: (2019)

Determination of the Minimum Sample Amount for Capillary Electrophoresis-Fourier Transform Mass Spectrometry (CE-FTMS)-Based Metabolomics of Colorectal Cancer Biopsies
por: Sugishita, Tetsuo, et al.
Publicado: (2023)

Comparison of short‐term outcomes between robot‐assisted and laparoscopic rectal surgery for rectal cancer: A propensity score‐matched analysis using the Japanese Nationwide diagnosis procedure combination database
por: Mizoguchi, Masako, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_518su45k6og45fjhnetsleqoe4