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Claspin-Dependent and -Independent Chk1 Activation by a Panel of Biological Stresses

Replication stress has been suggested to be an ultimate trigger of carcinogenesis. Oncogenic signal, such as overexpression of CyclinE, has been shown to induce replication stress. Here, we show that various biological stresses, including heat, oxidative stress, osmotic stress, LPS, hypoxia, and ars...

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Detalles Bibliográficos
Autores principales: Hsiao, Hao-Wen, Yang, Chi-Chun, Masai, Hisao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855620/
https://www.ncbi.nlm.nih.gov/pubmed/36671510
http://dx.doi.org/10.3390/biom13010125