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Poor Cognitive Agility Conservation in Obese Aging People

Life expectancy has been boosted in recent decades at expenses of increasing the age-associated diseases. Dementia, for its incidence, stands out among the pathologies associated with aging. The exacerbated cognitive deterioration disables people from carrying out their daily lives autonomously and...

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Autores principales: Pardo-Moreno, Teresa, Mohamed-Mohamed, Himan, Rivas-Dominguez, Antonio, Garcia-Morales, Victoria, Garcia-Lara, Ruben A., Suleiman-Martos, Sami, Bermudez-Pulgarin, Beatriz, Ramos-Rodriguez, Juan Jose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855664/
https://www.ncbi.nlm.nih.gov/pubmed/36672646
http://dx.doi.org/10.3390/biomedicines11010138
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author Pardo-Moreno, Teresa
Mohamed-Mohamed, Himan
Rivas-Dominguez, Antonio
Garcia-Morales, Victoria
Garcia-Lara, Ruben A.
Suleiman-Martos, Sami
Bermudez-Pulgarin, Beatriz
Ramos-Rodriguez, Juan Jose
author_facet Pardo-Moreno, Teresa
Mohamed-Mohamed, Himan
Rivas-Dominguez, Antonio
Garcia-Morales, Victoria
Garcia-Lara, Ruben A.
Suleiman-Martos, Sami
Bermudez-Pulgarin, Beatriz
Ramos-Rodriguez, Juan Jose
author_sort Pardo-Moreno, Teresa
collection PubMed
description Life expectancy has been boosted in recent decades at expenses of increasing the age-associated diseases. Dementia, for its incidence, stands out among the pathologies associated with aging. The exacerbated cognitive deterioration disables people from carrying out their daily lives autonomously and this incidence increases exponentially after 65 years of age. The etiology of dementia is a miscellaneous combination of risk factors that restrain the quality of life of our elderly. In this sense, it has been established that some metabolic pathologies such as obesity and diabetes act as a risk factor for dementia development. In contrast, a high educational level, as well as moderate physical activity, have been shown to be protective factors against cognitive impairment and the development of dementia. In the present study, we have evaluated the metabolic composition of a population between 60–90 years old, mentally healthy and with high academic degrees. After assessing agility in mental state, we have established relationships between their cognitive abilities and their body composition. Our data support that excess body fat is associated with poorer maintenance of cognition, while higher percentages of muscle mass are associated with the best results in the cognitive tests.
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spelling pubmed-98556642023-01-21 Poor Cognitive Agility Conservation in Obese Aging People Pardo-Moreno, Teresa Mohamed-Mohamed, Himan Rivas-Dominguez, Antonio Garcia-Morales, Victoria Garcia-Lara, Ruben A. Suleiman-Martos, Sami Bermudez-Pulgarin, Beatriz Ramos-Rodriguez, Juan Jose Biomedicines Article Life expectancy has been boosted in recent decades at expenses of increasing the age-associated diseases. Dementia, for its incidence, stands out among the pathologies associated with aging. The exacerbated cognitive deterioration disables people from carrying out their daily lives autonomously and this incidence increases exponentially after 65 years of age. The etiology of dementia is a miscellaneous combination of risk factors that restrain the quality of life of our elderly. In this sense, it has been established that some metabolic pathologies such as obesity and diabetes act as a risk factor for dementia development. In contrast, a high educational level, as well as moderate physical activity, have been shown to be protective factors against cognitive impairment and the development of dementia. In the present study, we have evaluated the metabolic composition of a population between 60–90 years old, mentally healthy and with high academic degrees. After assessing agility in mental state, we have established relationships between their cognitive abilities and their body composition. Our data support that excess body fat is associated with poorer maintenance of cognition, while higher percentages of muscle mass are associated with the best results in the cognitive tests. MDPI 2023-01-05 /pmc/articles/PMC9855664/ /pubmed/36672646 http://dx.doi.org/10.3390/biomedicines11010138 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Pardo-Moreno, Teresa
Mohamed-Mohamed, Himan
Rivas-Dominguez, Antonio
Garcia-Morales, Victoria
Garcia-Lara, Ruben A.
Suleiman-Martos, Sami
Bermudez-Pulgarin, Beatriz
Ramos-Rodriguez, Juan Jose
Poor Cognitive Agility Conservation in Obese Aging People
title Poor Cognitive Agility Conservation in Obese Aging People
title_full Poor Cognitive Agility Conservation in Obese Aging People
title_fullStr Poor Cognitive Agility Conservation in Obese Aging People
title_full_unstemmed Poor Cognitive Agility Conservation in Obese Aging People
title_short Poor Cognitive Agility Conservation in Obese Aging People
title_sort poor cognitive agility conservation in obese aging people
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855664/
https://www.ncbi.nlm.nih.gov/pubmed/36672646
http://dx.doi.org/10.3390/biomedicines11010138
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