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Design and Detection of Cyanide Raman Tag pH-Responsive SERS Probes
As one of the most important parameters of biochemical analysis and detection, the pH value plays a very important role in cell function, food preservation and production, soil and water sources, and other applications. This makes it increasingly important to explore pH detection methods in depth. I...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855686/ https://www.ncbi.nlm.nih.gov/pubmed/36671856 http://dx.doi.org/10.3390/bios13010021 |
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author | Shen, Jingjing Liu, Guan Zhang, Wen Shi, Wenwen Zhou, Yang Yu, Zejie Mei, Qunbo Zhang, Lei Huang, Wei |
author_facet | Shen, Jingjing Liu, Guan Zhang, Wen Shi, Wenwen Zhou, Yang Yu, Zejie Mei, Qunbo Zhang, Lei Huang, Wei |
author_sort | Shen, Jingjing |
collection | PubMed |
description | As one of the most important parameters of biochemical analysis and detection, the pH value plays a very important role in cell function, food preservation and production, soil and water sources, and other applications. This makes it increasingly important to explore pH detection methods in depth. In this paper, a pH-responsive SERS probe based on the cyano Raman Tag was designed to realize pH sensing detection through the influence of the pH value of analytes on the displacement of the cyano Raman peak in the SERS probe. This cyano Raman tag exhibited not only excellent sensitivity in the liner range of pH 3.0–9.0 with a limit of detection (LOD) of pH 0.33, but also the anti-interference performance and stability (the relative standard deviation (RSD) was calculated to be 6.68%, n = 5). These results indicated that this pH SERS probe with the Raman cyano tag can provide new research ideas for future biological detection, bioimaging, and environmental detection. |
format | Online Article Text |
id | pubmed-9855686 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-98556862023-01-21 Design and Detection of Cyanide Raman Tag pH-Responsive SERS Probes Shen, Jingjing Liu, Guan Zhang, Wen Shi, Wenwen Zhou, Yang Yu, Zejie Mei, Qunbo Zhang, Lei Huang, Wei Biosensors (Basel) Article As one of the most important parameters of biochemical analysis and detection, the pH value plays a very important role in cell function, food preservation and production, soil and water sources, and other applications. This makes it increasingly important to explore pH detection methods in depth. In this paper, a pH-responsive SERS probe based on the cyano Raman Tag was designed to realize pH sensing detection through the influence of the pH value of analytes on the displacement of the cyano Raman peak in the SERS probe. This cyano Raman tag exhibited not only excellent sensitivity in the liner range of pH 3.0–9.0 with a limit of detection (LOD) of pH 0.33, but also the anti-interference performance and stability (the relative standard deviation (RSD) was calculated to be 6.68%, n = 5). These results indicated that this pH SERS probe with the Raman cyano tag can provide new research ideas for future biological detection, bioimaging, and environmental detection. MDPI 2022-12-25 /pmc/articles/PMC9855686/ /pubmed/36671856 http://dx.doi.org/10.3390/bios13010021 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Shen, Jingjing Liu, Guan Zhang, Wen Shi, Wenwen Zhou, Yang Yu, Zejie Mei, Qunbo Zhang, Lei Huang, Wei Design and Detection of Cyanide Raman Tag pH-Responsive SERS Probes |
title | Design and Detection of Cyanide Raman Tag pH-Responsive SERS Probes |
title_full | Design and Detection of Cyanide Raman Tag pH-Responsive SERS Probes |
title_fullStr | Design and Detection of Cyanide Raman Tag pH-Responsive SERS Probes |
title_full_unstemmed | Design and Detection of Cyanide Raman Tag pH-Responsive SERS Probes |
title_short | Design and Detection of Cyanide Raman Tag pH-Responsive SERS Probes |
title_sort | design and detection of cyanide raman tag ph-responsive sers probes |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855686/ https://www.ncbi.nlm.nih.gov/pubmed/36671856 http://dx.doi.org/10.3390/bios13010021 |
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