Cargando…

Design and Detection of Cyanide Raman Tag pH-Responsive SERS Probes

As one of the most important parameters of biochemical analysis and detection, the pH value plays a very important role in cell function, food preservation and production, soil and water sources, and other applications. This makes it increasingly important to explore pH detection methods in depth. I...

Descripción completa

Detalles Bibliográficos
Autores principales: Shen, Jingjing, Liu, Guan, Zhang, Wen, Shi, Wenwen, Zhou, Yang, Yu, Zejie, Mei, Qunbo, Zhang, Lei, Huang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855686/
https://www.ncbi.nlm.nih.gov/pubmed/36671856
http://dx.doi.org/10.3390/bios13010021
_version_ 1784873437783654400
author Shen, Jingjing
Liu, Guan
Zhang, Wen
Shi, Wenwen
Zhou, Yang
Yu, Zejie
Mei, Qunbo
Zhang, Lei
Huang, Wei
author_facet Shen, Jingjing
Liu, Guan
Zhang, Wen
Shi, Wenwen
Zhou, Yang
Yu, Zejie
Mei, Qunbo
Zhang, Lei
Huang, Wei
author_sort Shen, Jingjing
collection PubMed
description As one of the most important parameters of biochemical analysis and detection, the pH value plays a very important role in cell function, food preservation and production, soil and water sources, and other applications. This makes it increasingly important to explore pH detection methods in depth. In this paper, a pH-responsive SERS probe based on the cyano Raman Tag was designed to realize pH sensing detection through the influence of the pH value of analytes on the displacement of the cyano Raman peak in the SERS probe. This cyano Raman tag exhibited not only excellent sensitivity in the liner range of pH 3.0–9.0 with a limit of detection (LOD) of pH 0.33, but also the anti-interference performance and stability (the relative standard deviation (RSD) was calculated to be 6.68%, n = 5). These results indicated that this pH SERS probe with the Raman cyano tag can provide new research ideas for future biological detection, bioimaging, and environmental detection.
format Online
Article
Text
id pubmed-9855686
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-98556862023-01-21 Design and Detection of Cyanide Raman Tag pH-Responsive SERS Probes Shen, Jingjing Liu, Guan Zhang, Wen Shi, Wenwen Zhou, Yang Yu, Zejie Mei, Qunbo Zhang, Lei Huang, Wei Biosensors (Basel) Article As one of the most important parameters of biochemical analysis and detection, the pH value plays a very important role in cell function, food preservation and production, soil and water sources, and other applications. This makes it increasingly important to explore pH detection methods in depth. In this paper, a pH-responsive SERS probe based on the cyano Raman Tag was designed to realize pH sensing detection through the influence of the pH value of analytes on the displacement of the cyano Raman peak in the SERS probe. This cyano Raman tag exhibited not only excellent sensitivity in the liner range of pH 3.0–9.0 with a limit of detection (LOD) of pH 0.33, but also the anti-interference performance and stability (the relative standard deviation (RSD) was calculated to be 6.68%, n = 5). These results indicated that this pH SERS probe with the Raman cyano tag can provide new research ideas for future biological detection, bioimaging, and environmental detection. MDPI 2022-12-25 /pmc/articles/PMC9855686/ /pubmed/36671856 http://dx.doi.org/10.3390/bios13010021 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Shen, Jingjing
Liu, Guan
Zhang, Wen
Shi, Wenwen
Zhou, Yang
Yu, Zejie
Mei, Qunbo
Zhang, Lei
Huang, Wei
Design and Detection of Cyanide Raman Tag pH-Responsive SERS Probes
title Design and Detection of Cyanide Raman Tag pH-Responsive SERS Probes
title_full Design and Detection of Cyanide Raman Tag pH-Responsive SERS Probes
title_fullStr Design and Detection of Cyanide Raman Tag pH-Responsive SERS Probes
title_full_unstemmed Design and Detection of Cyanide Raman Tag pH-Responsive SERS Probes
title_short Design and Detection of Cyanide Raman Tag pH-Responsive SERS Probes
title_sort design and detection of cyanide raman tag ph-responsive sers probes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855686/
https://www.ncbi.nlm.nih.gov/pubmed/36671856
http://dx.doi.org/10.3390/bios13010021
work_keys_str_mv AT shenjingjing designanddetectionofcyanideramantagphresponsivesersprobes
AT liuguan designanddetectionofcyanideramantagphresponsivesersprobes
AT zhangwen designanddetectionofcyanideramantagphresponsivesersprobes
AT shiwenwen designanddetectionofcyanideramantagphresponsivesersprobes
AT zhouyang designanddetectionofcyanideramantagphresponsivesersprobes
AT yuzejie designanddetectionofcyanideramantagphresponsivesersprobes
AT meiqunbo designanddetectionofcyanideramantagphresponsivesersprobes
AT zhanglei designanddetectionofcyanideramantagphresponsivesersprobes
AT huangwei designanddetectionofcyanideramantagphresponsivesersprobes