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Genetic Predisposition to Neurological Complications in Patients with COVID-19
Several studies have identified rare and common genetic variants associated with severe COVID-19, but no study has reported genetic determinants as predisposition factors for neurological complications. In this report, we identified rare/unique structural variants (SVs) implicated in neurological fu...
| Autores principales: | , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855758/ https://www.ncbi.nlm.nih.gov/pubmed/36671517 http://dx.doi.org/10.3390/biom13010133 |
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| author | Sahajpal, Nikhil Shri Hastie, Alex R. Schieck, Maximilian Mondal, Ashis K. Felde, Marc van der Made, Caspar I. Chou, Janet S. Randolph, Adrienne G. Illig, Thomas Zody, Michael C. Brownstein, Catherine A. Beggs, Alan H. Hoischen, Alexander Chaubey, Alka Kolhe, Ravindra |
| author_facet | Sahajpal, Nikhil Shri Hastie, Alex R. Schieck, Maximilian Mondal, Ashis K. Felde, Marc van der Made, Caspar I. Chou, Janet S. Randolph, Adrienne G. Illig, Thomas Zody, Michael C. Brownstein, Catherine A. Beggs, Alan H. Hoischen, Alexander Chaubey, Alka Kolhe, Ravindra |
| author_sort | Sahajpal, Nikhil Shri |
| collection | PubMed |
| description | Several studies have identified rare and common genetic variants associated with severe COVID-19, but no study has reported genetic determinants as predisposition factors for neurological complications. In this report, we identified rare/unique structural variants (SVs) implicated in neurological functions in two individuals with neurological manifestations of COVID-19. This report highlights the possible genetic link to the neurological symptoms with COVID-19 and calls for a collective effort to study these cohorts for a possible genetic linkage. |
| format | Online Article Text |
| id | pubmed-9855758 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2023 |
| publisher | MDPI |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-98557582023-01-21 Genetic Predisposition to Neurological Complications in Patients with COVID-19 Sahajpal, Nikhil Shri Hastie, Alex R. Schieck, Maximilian Mondal, Ashis K. Felde, Marc van der Made, Caspar I. Chou, Janet S. Randolph, Adrienne G. Illig, Thomas Zody, Michael C. Brownstein, Catherine A. Beggs, Alan H. Hoischen, Alexander Chaubey, Alka Kolhe, Ravindra Biomolecules Brief Report Several studies have identified rare and common genetic variants associated with severe COVID-19, but no study has reported genetic determinants as predisposition factors for neurological complications. In this report, we identified rare/unique structural variants (SVs) implicated in neurological functions in two individuals with neurological manifestations of COVID-19. This report highlights the possible genetic link to the neurological symptoms with COVID-19 and calls for a collective effort to study these cohorts for a possible genetic linkage. MDPI 2023-01-09 /pmc/articles/PMC9855758/ /pubmed/36671517 http://dx.doi.org/10.3390/biom13010133 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
| spellingShingle | Brief Report Sahajpal, Nikhil Shri Hastie, Alex R. Schieck, Maximilian Mondal, Ashis K. Felde, Marc van der Made, Caspar I. Chou, Janet S. Randolph, Adrienne G. Illig, Thomas Zody, Michael C. Brownstein, Catherine A. Beggs, Alan H. Hoischen, Alexander Chaubey, Alka Kolhe, Ravindra Genetic Predisposition to Neurological Complications in Patients with COVID-19 |
| title | Genetic Predisposition to Neurological Complications in Patients with COVID-19 |
| title_full | Genetic Predisposition to Neurological Complications in Patients with COVID-19 |
| title_fullStr | Genetic Predisposition to Neurological Complications in Patients with COVID-19 |
| title_full_unstemmed | Genetic Predisposition to Neurological Complications in Patients with COVID-19 |
| title_short | Genetic Predisposition to Neurological Complications in Patients with COVID-19 |
| title_sort | genetic predisposition to neurological complications in patients with covid-19 |
| topic | Brief Report |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855758/ https://www.ncbi.nlm.nih.gov/pubmed/36671517 http://dx.doi.org/10.3390/biom13010133 |
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