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Effects of Transient Administration of the NMDA Receptor Antagonist MK-801 in Drosophila melanogaster Activity, Sleep, and Negative Geotaxis
MK-801, also called dizocilpine, is an N-methyl-D-aspartate (NMDA) receptor antagonist widely used in animal research to model schizophrenia-like phenotypes. Although its effects in rodents are well characterised, little is known about the outcomes of this drug in other organisms. In this study, we...
Autores principales: | Moulin, Thiago C., Stojanovic, Tijana, Rajesh, Rasika P., Pareek, Tirusha, Donzelli, Laura, Williams, Michael J., Schiöth, Helgi B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855773/ https://www.ncbi.nlm.nih.gov/pubmed/36672700 http://dx.doi.org/10.3390/biomedicines11010192 |
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