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Effects of Transient Administration of the NMDA Receptor Antagonist MK-801 in Drosophila melanogaster Activity, Sleep, and Negative Geotaxis

MK-801, also called dizocilpine, is an N-methyl-D-aspartate (NMDA) receptor antagonist widely used in animal research to model schizophrenia-like phenotypes. Although its effects in rodents are well characterised, little is known about the outcomes of this drug in other organisms. In this study, we...

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Detalles Bibliográficos
Autores principales: Moulin, Thiago C., Stojanovic, Tijana, Rajesh, Rasika P., Pareek, Tirusha, Donzelli, Laura, Williams, Michael J., Schiöth, Helgi B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855773/
https://www.ncbi.nlm.nih.gov/pubmed/36672700
http://dx.doi.org/10.3390/biomedicines11010192

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