Cargando…
Recent Progress of Electrospun Herbal Medicine Nanofibers
Herbal medicine has a long history of medical efficacy with low toxicity, side effects and good biocompatibility. However, the bioavailability of the extract of raw herbs and bioactive compounds is poor because of their low water solubility. In order to overcome the solubility issues, electrospinnin...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855805/ https://www.ncbi.nlm.nih.gov/pubmed/36671570 http://dx.doi.org/10.3390/biom13010184 |
_version_ | 1784873465535266816 |
---|---|
author | Liu, Hang Bai, Yubin Huang, Chang Wang, Ying Ji, Yuexin Du, Yutong Xu, Lin Yu, Deng-Guang Bligh, Sim Wan Annie |
author_facet | Liu, Hang Bai, Yubin Huang, Chang Wang, Ying Ji, Yuexin Du, Yutong Xu, Lin Yu, Deng-Guang Bligh, Sim Wan Annie |
author_sort | Liu, Hang |
collection | PubMed |
description | Herbal medicine has a long history of medical efficacy with low toxicity, side effects and good biocompatibility. However, the bioavailability of the extract of raw herbs and bioactive compounds is poor because of their low water solubility. In order to overcome the solubility issues, electrospinning technology can offer a delivery alternative to resolve them. The electrospun fibers have the advantages of high specific surface area, high porosity, excellent mechanical strength and flexible structures. At the same time, various natural and synthetic polymer-bound fibers can mimic extracellular matrix applications in different medical fields. In this paper, the development of electrospinning technology and polymers used for incorporating herbal medicine into electrospun nanofibers are reviewed. Finally, the recent progress of the applications of these herbal medicine nanofibers in biomedical (drug delivery, wound dressing, tissue engineering) and food fields along with their future prospects is discussed. |
format | Online Article Text |
id | pubmed-9855805 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-98558052023-01-21 Recent Progress of Electrospun Herbal Medicine Nanofibers Liu, Hang Bai, Yubin Huang, Chang Wang, Ying Ji, Yuexin Du, Yutong Xu, Lin Yu, Deng-Guang Bligh, Sim Wan Annie Biomolecules Review Herbal medicine has a long history of medical efficacy with low toxicity, side effects and good biocompatibility. However, the bioavailability of the extract of raw herbs and bioactive compounds is poor because of their low water solubility. In order to overcome the solubility issues, electrospinning technology can offer a delivery alternative to resolve them. The electrospun fibers have the advantages of high specific surface area, high porosity, excellent mechanical strength and flexible structures. At the same time, various natural and synthetic polymer-bound fibers can mimic extracellular matrix applications in different medical fields. In this paper, the development of electrospinning technology and polymers used for incorporating herbal medicine into electrospun nanofibers are reviewed. Finally, the recent progress of the applications of these herbal medicine nanofibers in biomedical (drug delivery, wound dressing, tissue engineering) and food fields along with their future prospects is discussed. MDPI 2023-01-16 /pmc/articles/PMC9855805/ /pubmed/36671570 http://dx.doi.org/10.3390/biom13010184 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Liu, Hang Bai, Yubin Huang, Chang Wang, Ying Ji, Yuexin Du, Yutong Xu, Lin Yu, Deng-Guang Bligh, Sim Wan Annie Recent Progress of Electrospun Herbal Medicine Nanofibers |
title | Recent Progress of Electrospun Herbal Medicine Nanofibers |
title_full | Recent Progress of Electrospun Herbal Medicine Nanofibers |
title_fullStr | Recent Progress of Electrospun Herbal Medicine Nanofibers |
title_full_unstemmed | Recent Progress of Electrospun Herbal Medicine Nanofibers |
title_short | Recent Progress of Electrospun Herbal Medicine Nanofibers |
title_sort | recent progress of electrospun herbal medicine nanofibers |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855805/ https://www.ncbi.nlm.nih.gov/pubmed/36671570 http://dx.doi.org/10.3390/biom13010184 |
work_keys_str_mv | AT liuhang recentprogressofelectrospunherbalmedicinenanofibers AT baiyubin recentprogressofelectrospunherbalmedicinenanofibers AT huangchang recentprogressofelectrospunherbalmedicinenanofibers AT wangying recentprogressofelectrospunherbalmedicinenanofibers AT jiyuexin recentprogressofelectrospunherbalmedicinenanofibers AT duyutong recentprogressofelectrospunherbalmedicinenanofibers AT xulin recentprogressofelectrospunherbalmedicinenanofibers AT yudengguang recentprogressofelectrospunherbalmedicinenanofibers AT blighsimwanannie recentprogressofelectrospunherbalmedicinenanofibers |