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Recent Progress of Electrospun Herbal Medicine Nanofibers

Herbal medicine has a long history of medical efficacy with low toxicity, side effects and good biocompatibility. However, the bioavailability of the extract of raw herbs and bioactive compounds is poor because of their low water solubility. In order to overcome the solubility issues, electrospinnin...

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Detalles Bibliográficos
Autores principales: Liu, Hang, Bai, Yubin, Huang, Chang, Wang, Ying, Ji, Yuexin, Du, Yutong, Xu, Lin, Yu, Deng-Guang, Bligh, Sim Wan Annie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855805/
https://www.ncbi.nlm.nih.gov/pubmed/36671570
http://dx.doi.org/10.3390/biom13010184
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author Liu, Hang
Bai, Yubin
Huang, Chang
Wang, Ying
Ji, Yuexin
Du, Yutong
Xu, Lin
Yu, Deng-Guang
Bligh, Sim Wan Annie
author_facet Liu, Hang
Bai, Yubin
Huang, Chang
Wang, Ying
Ji, Yuexin
Du, Yutong
Xu, Lin
Yu, Deng-Guang
Bligh, Sim Wan Annie
author_sort Liu, Hang
collection PubMed
description Herbal medicine has a long history of medical efficacy with low toxicity, side effects and good biocompatibility. However, the bioavailability of the extract of raw herbs and bioactive compounds is poor because of their low water solubility. In order to overcome the solubility issues, electrospinning technology can offer a delivery alternative to resolve them. The electrospun fibers have the advantages of high specific surface area, high porosity, excellent mechanical strength and flexible structures. At the same time, various natural and synthetic polymer-bound fibers can mimic extracellular matrix applications in different medical fields. In this paper, the development of electrospinning technology and polymers used for incorporating herbal medicine into electrospun nanofibers are reviewed. Finally, the recent progress of the applications of these herbal medicine nanofibers in biomedical (drug delivery, wound dressing, tissue engineering) and food fields along with their future prospects is discussed.
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spelling pubmed-98558052023-01-21 Recent Progress of Electrospun Herbal Medicine Nanofibers Liu, Hang Bai, Yubin Huang, Chang Wang, Ying Ji, Yuexin Du, Yutong Xu, Lin Yu, Deng-Guang Bligh, Sim Wan Annie Biomolecules Review Herbal medicine has a long history of medical efficacy with low toxicity, side effects and good biocompatibility. However, the bioavailability of the extract of raw herbs and bioactive compounds is poor because of their low water solubility. In order to overcome the solubility issues, electrospinning technology can offer a delivery alternative to resolve them. The electrospun fibers have the advantages of high specific surface area, high porosity, excellent mechanical strength and flexible structures. At the same time, various natural and synthetic polymer-bound fibers can mimic extracellular matrix applications in different medical fields. In this paper, the development of electrospinning technology and polymers used for incorporating herbal medicine into electrospun nanofibers are reviewed. Finally, the recent progress of the applications of these herbal medicine nanofibers in biomedical (drug delivery, wound dressing, tissue engineering) and food fields along with their future prospects is discussed. MDPI 2023-01-16 /pmc/articles/PMC9855805/ /pubmed/36671570 http://dx.doi.org/10.3390/biom13010184 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Liu, Hang
Bai, Yubin
Huang, Chang
Wang, Ying
Ji, Yuexin
Du, Yutong
Xu, Lin
Yu, Deng-Guang
Bligh, Sim Wan Annie
Recent Progress of Electrospun Herbal Medicine Nanofibers
title Recent Progress of Electrospun Herbal Medicine Nanofibers
title_full Recent Progress of Electrospun Herbal Medicine Nanofibers
title_fullStr Recent Progress of Electrospun Herbal Medicine Nanofibers
title_full_unstemmed Recent Progress of Electrospun Herbal Medicine Nanofibers
title_short Recent Progress of Electrospun Herbal Medicine Nanofibers
title_sort recent progress of electrospun herbal medicine nanofibers
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855805/
https://www.ncbi.nlm.nih.gov/pubmed/36671570
http://dx.doi.org/10.3390/biom13010184
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