A Mitochondrion-Targeting Protein (B2) Primes ROS/Nrf2-Mediated Stress Signals, Triggering Apoptosis and Necroptosis in Lung Cancer

The betanodavirus B2 protein targets mitochondria and triggers mitochondrion-mediated cell death signaling in lung cancer cells; however, its molecular mechanism remains unknown. In this study, we observed that B2 triggers hydrogen peroxide/Nrf2-involved stress signals in the dynamic regulation of n...

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Detalles Bibliográficos
Autores principales: Chiu, Hsuan-Wen, Hung, Shao-Wen, Chiu, Ching-Feng, Hong, Jiann-Ruey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855812/
https://www.ncbi.nlm.nih.gov/pubmed/36672696
http://dx.doi.org/10.3390/biomedicines11010186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855812/
https://www.ncbi.nlm.nih.gov/pubmed/36672696
http://dx.doi.org/10.3390/biomedicines11010186

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