Cargando…
3α,7-Dihydroxy-14(13→12)abeo-5β,12α(H),13β(H)-cholan-24-oic Acids Display Neuroprotective Properties in Common Forms of Parkinson’s Disease
Parkinson’s Disease is the most common neurodegenerative movement disorder globally, with prevalence increasing. There is an urgent need for new therapeutics which are disease-modifying rather than symptomatic. Mitochondrial dysfunction is a well-documented mechanism in both sporadic and familial Pa...
Autores principales: | Luxenburger, Andreas, Clemmens, Hannah, Hastings, Christopher, Harris, Lawrence D., Ure, Elizabeth M., Cameron, Scott A., Aasly, Jan, Bandmann, Oliver, Weymouth-Wilson, Alex, Furneaux, Richard H., Mortiboys, Heather |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855844/ https://www.ncbi.nlm.nih.gov/pubmed/36671460 http://dx.doi.org/10.3390/biom13010076 |
Ejemplares similares
-
Synthesis of 12β-Methyl-18-nor-bile Acids
por: Luxenburger, Andreas, et al.
Publicado: (2021) -
pH-Sensitive Liposomes with Embedded 3-(isobutylamino)cholan-24-oic Acid: What Is the Possible Mechanism of Fast Cargo Release?
por: Efimova, Anna A., et al.
Publicado: (2023) -
Diels-Alder Reactions of 12-Hydroxy-9(10→20)-5aH-abeo-abieta-1(10),8(9),12(13)-triene-11,14-dione
por: Majetich, George, et al.
Publicado: (2013) -
Camptothecin-20(s)-O-[N-(3’α,12’α-dihydroxy-24’-carbonyl-5’β-cholan)]-lysine, a Novel Camptothecin Analogue, Induces Apoptosis towards Hepatocellular Carcinoma SMMC-7721 Cells
por: Li, Qingyong, et al.
Publicado: (2011) -
Bis[3α,7α,12α-tris(4-nitrobenzoyloxy)-5β-cholan-24-yl] disulfide–ethyl acetate–n-hexane (4/4/1)
por: Brzezinski, Krzysztof, et al.
Publicado: (2010)