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Multifrequency Microwave Radiometry for Characterizing the Internal Temperature of Biological Tissues

The analysis of near-field radiometry is described for characterizing the internal temperature of biological tissues, for which a system based on multifrequency pseudo-correlation-type radiometers is proposed. The approach consists of a new topology with multiple output devices that enables real-tim...

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Autores principales: Villa, Enrique, Aja, Beatriz, de la Fuente, Luisa, Artal, Eduardo, Arteaga-Marrero, Natalia, Ramos, Gara, Ruiz-Alzola, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855903/
https://www.ncbi.nlm.nih.gov/pubmed/36671860
http://dx.doi.org/10.3390/bios13010025
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author Villa, Enrique
Aja, Beatriz
de la Fuente, Luisa
Artal, Eduardo
Arteaga-Marrero, Natalia
Ramos, Gara
Ruiz-Alzola, Juan
author_facet Villa, Enrique
Aja, Beatriz
de la Fuente, Luisa
Artal, Eduardo
Arteaga-Marrero, Natalia
Ramos, Gara
Ruiz-Alzola, Juan
author_sort Villa, Enrique
collection PubMed
description The analysis of near-field radiometry is described for characterizing the internal temperature of biological tissues, for which a system based on multifrequency pseudo-correlation-type radiometers is proposed. The approach consists of a new topology with multiple output devices that enables real-time calibration and performance assessment, recalibrating the receiver through simultaneous measurable outputs. Experimental characterization of the prototypes includes a well-defined calibration procedure, which is described and demonstrated, as well as DC conversion from the microwave input power. Regarding performance, high sensitivity is provided in all the bands with noise temperatures around 100 K, reducing the impact of the receiver on the measurements and improving its sensitivity. Calibrated temperature retrievals exhibit outstanding results for several noise sources, for which temperature deviations are lower than 0.1% with regard to the expected temperature. Furthermore, a temperature recovery test for biological tissues, such as a human forearm, provides temperature values on the order of 310 K. In summary, the radiometers design, calibration method and temperature retrieval demonstrated significant results in all bands, validating their use for biomedical applications.
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spelling pubmed-98559032023-01-21 Multifrequency Microwave Radiometry for Characterizing the Internal Temperature of Biological Tissues Villa, Enrique Aja, Beatriz de la Fuente, Luisa Artal, Eduardo Arteaga-Marrero, Natalia Ramos, Gara Ruiz-Alzola, Juan Biosensors (Basel) Article The analysis of near-field radiometry is described for characterizing the internal temperature of biological tissues, for which a system based on multifrequency pseudo-correlation-type radiometers is proposed. The approach consists of a new topology with multiple output devices that enables real-time calibration and performance assessment, recalibrating the receiver through simultaneous measurable outputs. Experimental characterization of the prototypes includes a well-defined calibration procedure, which is described and demonstrated, as well as DC conversion from the microwave input power. Regarding performance, high sensitivity is provided in all the bands with noise temperatures around 100 K, reducing the impact of the receiver on the measurements and improving its sensitivity. Calibrated temperature retrievals exhibit outstanding results for several noise sources, for which temperature deviations are lower than 0.1% with regard to the expected temperature. Furthermore, a temperature recovery test for biological tissues, such as a human forearm, provides temperature values on the order of 310 K. In summary, the radiometers design, calibration method and temperature retrieval demonstrated significant results in all bands, validating their use for biomedical applications. MDPI 2022-12-26 /pmc/articles/PMC9855903/ /pubmed/36671860 http://dx.doi.org/10.3390/bios13010025 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Villa, Enrique
Aja, Beatriz
de la Fuente, Luisa
Artal, Eduardo
Arteaga-Marrero, Natalia
Ramos, Gara
Ruiz-Alzola, Juan
Multifrequency Microwave Radiometry for Characterizing the Internal Temperature of Biological Tissues
title Multifrequency Microwave Radiometry for Characterizing the Internal Temperature of Biological Tissues
title_full Multifrequency Microwave Radiometry for Characterizing the Internal Temperature of Biological Tissues
title_fullStr Multifrequency Microwave Radiometry for Characterizing the Internal Temperature of Biological Tissues
title_full_unstemmed Multifrequency Microwave Radiometry for Characterizing the Internal Temperature of Biological Tissues
title_short Multifrequency Microwave Radiometry for Characterizing the Internal Temperature of Biological Tissues
title_sort multifrequency microwave radiometry for characterizing the internal temperature of biological tissues
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855903/
https://www.ncbi.nlm.nih.gov/pubmed/36671860
http://dx.doi.org/10.3390/bios13010025
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