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TGF-Beta Modulates the Integrity of the Blood Brain Barrier In Vitro, and Is Associated with Metabolic Alterations in Pericytes

The blood–brain barrier (BBB) is a selectively permeable boundary that separates the circulating blood from the extracellular fluid of the brain and is an essential component for brain homeostasis. In glioblastoma (GBM), the BBB of peritumoral vessels is often disrupted. Pericytes, being important t...

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Detalles Bibliográficos
Autores principales: Schumacher, Leonie, Slimani, Rédouane, Zizmare, Laimdota, Ehlers, Jakob, Kleine Borgmann, Felix, Fitzgerald, Julia C., Fallier-Becker, Petra, Beckmann, Anja, Grißmer, Alexander, Meier, Carola, El-Ayoubi, Ali, Devraj, Kavi, Mittelbronn, Michel, Trautwein, Christoph, Naumann, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855966/
https://www.ncbi.nlm.nih.gov/pubmed/36672722
http://dx.doi.org/10.3390/biomedicines11010214

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