FK506-Binding Protein 2 Participates in Proinsulin Folding

Apart from chaperoning, disulfide bond formation, and downstream processing, the molecular sequence of proinsulin folding is not completely understood. Proinsulin requires proline isomerization for correct folding. Since FK506-binding protein 2 (FKBP2) is an ER-resident proline isomerase, we hypothe...

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Detalles Bibliográficos
Autores principales: Hoefner, Carolin, Bryde, Tenna Holgersen, Pihl, Celina, Tiedemann, Sylvia Naiga, Bresson, Sophie Emilie, Hotiana, Hajira Ahmed, Khilji, Muhammad Saad, Santos, Theodore Dos, Puglia, Michele, Pisano, Paola, Majewska, Mariola, Durzynska, Julia, Klindt, Kristian, Klusek, Justyna, Perone, Marcelo J., Bucki, Robert, Hägglund, Per Mårten, Gourdon, Pontus Emanuel, Gotfryd, Kamil, Urbaniak, Edyta, Borowiak, Malgorzata, Wierer, Michael, MacDonald, Patrick Edward, Mandrup-Poulsen, Thomas, Marzec, Michal Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9855983/
https://www.ncbi.nlm.nih.gov/pubmed/36671537
http://dx.doi.org/10.3390/biom13010152

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