Cargando…
Age- and Sex-Dependent Behavioral and Neurochemical Alterations in hLRRK2-G2019S BAC Mice
The G2019S mutation in the leucine-rich repeat kinase 2 (LRRK2) gene is associated with late-onset Parkinson’s disease (PD). Although PD affects men and women differently, longitudinal studies examining sex- and age-dependent alterations in mice carrying the G2019S mutation are limited. We examined...
Autores principales: | Yao, Ning, Skiteva, Olga, Chergui, Karima |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856037/ https://www.ncbi.nlm.nih.gov/pubmed/36671436 http://dx.doi.org/10.3390/biom13010051 |
Ejemplares similares
-
LRRK2‐G2019S mice display alterations in glutamatergic synaptic transmission in midbrain dopamine neurons
por: Skiteva, Olga, et al.
Publicado: (2022) -
Neuronal Firing and Glutamatergic Synapses in the Substantia Nigra Pars Reticulata of LRRK2-G2019S Mice
por: Sitzia, Giacomo, et al.
Publicado: (2022) -
Aberrant somatic calcium channel function in cNurr1 and LRRK2-G2019S mice
por: Skiteva, Olga, et al.
Publicado: (2023) -
Ketamine induces opposite changes in AMPA receptor calcium permeability in the ventral tegmental area and nucleus accumbens
por: Skiteva, Olga, et al.
Publicado: (2021) -
Sex differences in LRRK2 G2019S and idiopathic Parkinson's Disease
por: San Luciano, Marta, et al.
Publicado: (2017)