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CIGB-300 Anticancer Peptide Differentially Interacts with CK2 Subunits and Regulates Specific Signaling Mediators in a Highly Sensitive Large Cell Lung Carcinoma Cell Model

Large cell lung carcinoma (LCLC) is one form of NSCLC that spreads more aggressively than some other forms, and it represents an unmet medical need. Here, we investigated for the first time the effect of the anti-CK2 CIGB-300 peptide in NCI-H460 cells as an LCLC model. NCI-H460 cells were highly sen...

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Detalles Bibliográficos
Autores principales: Pérez, George V., Rosales, Mauro, Ramón, Ailyn C., Rodríguez-Ulloa, Arielis, Besada, Vladimir, González, Luis J., Aguilar, Daylen, Vázquez-Blomquist, Dania, Falcón, Viviana, Caballero, Evelin, Carvalho, Paulo C., Caldeira, Rodrigo Soares, Yang, Ke, Perera, Yasser, Perea, Silvio E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856093/
https://www.ncbi.nlm.nih.gov/pubmed/36672551
http://dx.doi.org/10.3390/biomedicines11010043

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