Cargando…
Value of Antibody Determinations in Chronic Dysimmune Neuropathies
Chronic dysimmune neuropathies encompass a group of neuropathies that share immune-mediated pathomechanism. Chronic dysimmune antibody-related neuropathies include anti-MAG neuropathy, multifocal motor neuropathy, and neuropathies related to immune attack against paranodal antigens. Such neuropathie...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856104/ https://www.ncbi.nlm.nih.gov/pubmed/36672019 http://dx.doi.org/10.3390/brainsci13010037 |
_version_ | 1784873541323194368 |
---|---|
author | Tozza, Stefano Spina, Emanuele Iovino, Aniello Iodice, Rosa Dubbioso, Raffaele Ruggiero, Lucia Nolano, Maria Manganelli, Fiore |
author_facet | Tozza, Stefano Spina, Emanuele Iovino, Aniello Iodice, Rosa Dubbioso, Raffaele Ruggiero, Lucia Nolano, Maria Manganelli, Fiore |
author_sort | Tozza, Stefano |
collection | PubMed |
description | Chronic dysimmune neuropathies encompass a group of neuropathies that share immune-mediated pathomechanism. Chronic dysimmune antibody-related neuropathies include anti-MAG neuropathy, multifocal motor neuropathy, and neuropathies related to immune attack against paranodal antigens. Such neuropathies exhibit distinguishing pathomechanism, clinical and response to therapy features with respect to chronic inflammatory demyelinating polyradiculoneuropathy and its variants, which represent the most frequent form of chronic dysimmune neuropathy. This narrative review provides an overview of pathomechanism; clinical, electrophysiological, and biochemical features; and treatment response of the antibody-mediated neuropathies, aiming to establish when and why to look for antibodies in chronic dysimmune neuropathies. |
format | Online Article Text |
id | pubmed-9856104 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-98561042023-01-21 Value of Antibody Determinations in Chronic Dysimmune Neuropathies Tozza, Stefano Spina, Emanuele Iovino, Aniello Iodice, Rosa Dubbioso, Raffaele Ruggiero, Lucia Nolano, Maria Manganelli, Fiore Brain Sci Review Chronic dysimmune neuropathies encompass a group of neuropathies that share immune-mediated pathomechanism. Chronic dysimmune antibody-related neuropathies include anti-MAG neuropathy, multifocal motor neuropathy, and neuropathies related to immune attack against paranodal antigens. Such neuropathies exhibit distinguishing pathomechanism, clinical and response to therapy features with respect to chronic inflammatory demyelinating polyradiculoneuropathy and its variants, which represent the most frequent form of chronic dysimmune neuropathy. This narrative review provides an overview of pathomechanism; clinical, electrophysiological, and biochemical features; and treatment response of the antibody-mediated neuropathies, aiming to establish when and why to look for antibodies in chronic dysimmune neuropathies. MDPI 2022-12-23 /pmc/articles/PMC9856104/ /pubmed/36672019 http://dx.doi.org/10.3390/brainsci13010037 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Tozza, Stefano Spina, Emanuele Iovino, Aniello Iodice, Rosa Dubbioso, Raffaele Ruggiero, Lucia Nolano, Maria Manganelli, Fiore Value of Antibody Determinations in Chronic Dysimmune Neuropathies |
title | Value of Antibody Determinations in Chronic Dysimmune Neuropathies |
title_full | Value of Antibody Determinations in Chronic Dysimmune Neuropathies |
title_fullStr | Value of Antibody Determinations in Chronic Dysimmune Neuropathies |
title_full_unstemmed | Value of Antibody Determinations in Chronic Dysimmune Neuropathies |
title_short | Value of Antibody Determinations in Chronic Dysimmune Neuropathies |
title_sort | value of antibody determinations in chronic dysimmune neuropathies |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856104/ https://www.ncbi.nlm.nih.gov/pubmed/36672019 http://dx.doi.org/10.3390/brainsci13010037 |
work_keys_str_mv | AT tozzastefano valueofantibodydeterminationsinchronicdysimmuneneuropathies AT spinaemanuele valueofantibodydeterminationsinchronicdysimmuneneuropathies AT iovinoaniello valueofantibodydeterminationsinchronicdysimmuneneuropathies AT iodicerosa valueofantibodydeterminationsinchronicdysimmuneneuropathies AT dubbiosoraffaele valueofantibodydeterminationsinchronicdysimmuneneuropathies AT ruggierolucia valueofantibodydeterminationsinchronicdysimmuneneuropathies AT nolanomaria valueofantibodydeterminationsinchronicdysimmuneneuropathies AT manganellifiore valueofantibodydeterminationsinchronicdysimmuneneuropathies |