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Impact of Hypermannosylation on the Structure and Functionality of the ER and the Golgi Complex

Proteins of the secretory pathway undergo glycosylation in the endoplasmic reticulum (ER) and the Golgi apparatus. Altered protein glycosylation can manifest in serious, sometimes fatal malfunctions. We recently showed that mutations in GDP-mannose pyrophosphorylase A (GMPPA) can cause a syndrome ch...

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Detalles Bibliográficos
Autores principales:	Franzka, Patricia, Schüler, Svenja Caren, Kentache, Takfarinas, Storm, Robert, Bock, Andrea, Katona, Istvan, Weis, Joachim, Buder, Katrin, Kaether, Christoph, Hübner, Christian A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856158/ https://www.ncbi.nlm.nih.gov/pubmed/36672654 http://dx.doi.org/10.3390/biomedicines11010146

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