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Safety of Vaccination within First Year of Life—The Experience of One General Medicine Center

Vaccines represent an important preventive strategy in paediatric populations, but the rate of vaccination has been constantly declining in the last decade. Concerns about vaccines’ safety represent one of the main causes of vaccine hesitancy among parents. The aim of this study was the analysis of...

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Autores principales: Pop, Claudia Felicia, Coblisan, Petronela, Capalna, Ligia, Panța, Paraschiva Cherecheș, Buzoianu, Anca Dana, Bocsan, Ioana Corina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856298/
https://www.ncbi.nlm.nih.gov/pubmed/36670654
http://dx.doi.org/10.3390/children10010104
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author Pop, Claudia Felicia
Coblisan, Petronela
Capalna, Ligia
Panța, Paraschiva Cherecheș
Buzoianu, Anca Dana
Bocsan, Ioana Corina
author_facet Pop, Claudia Felicia
Coblisan, Petronela
Capalna, Ligia
Panța, Paraschiva Cherecheș
Buzoianu, Anca Dana
Bocsan, Ioana Corina
author_sort Pop, Claudia Felicia
collection PubMed
description Vaccines represent an important preventive strategy in paediatric populations, but the rate of vaccination has been constantly declining in the last decade. Concerns about vaccines’ safety represent one of the main causes of vaccine hesitancy among parents. The aim of this study was the analysis of the immediate adverse reactions induced by vaccines included in the national program of immunization for the first year of life. Method: Eighty-one children born between 1st of January 2018 and 31st of March 2019 were included. The vaccination refusal rate, and incidence and severity of adverse effects induced by three mandatory vaccines (Hexavalent, Prevenar 13 and MMR) were analyzed. The level of parents’ education and the sources of information that were consulted in order to understand the adverse effects were also analyzed. Results and conclusions: The rate of adverse events was lower than 30% of the total number of doses, and most of them were mild. The incidence and severity of vaccine-induced adverse effects were correlated with prematurity. The vaccine hesitancy rate was lower than the national one, possibly due to a high level of education and good information provided by doctors that might have led to parents’ concerns regarding vaccination being answered.
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spelling pubmed-98562982023-01-21 Safety of Vaccination within First Year of Life—The Experience of One General Medicine Center Pop, Claudia Felicia Coblisan, Petronela Capalna, Ligia Panța, Paraschiva Cherecheș Buzoianu, Anca Dana Bocsan, Ioana Corina Children (Basel) Article Vaccines represent an important preventive strategy in paediatric populations, but the rate of vaccination has been constantly declining in the last decade. Concerns about vaccines’ safety represent one of the main causes of vaccine hesitancy among parents. The aim of this study was the analysis of the immediate adverse reactions induced by vaccines included in the national program of immunization for the first year of life. Method: Eighty-one children born between 1st of January 2018 and 31st of March 2019 were included. The vaccination refusal rate, and incidence and severity of adverse effects induced by three mandatory vaccines (Hexavalent, Prevenar 13 and MMR) were analyzed. The level of parents’ education and the sources of information that were consulted in order to understand the adverse effects were also analyzed. Results and conclusions: The rate of adverse events was lower than 30% of the total number of doses, and most of them were mild. The incidence and severity of vaccine-induced adverse effects were correlated with prematurity. The vaccine hesitancy rate was lower than the national one, possibly due to a high level of education and good information provided by doctors that might have led to parents’ concerns regarding vaccination being answered. MDPI 2023-01-04 /pmc/articles/PMC9856298/ /pubmed/36670654 http://dx.doi.org/10.3390/children10010104 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Pop, Claudia Felicia
Coblisan, Petronela
Capalna, Ligia
Panța, Paraschiva Cherecheș
Buzoianu, Anca Dana
Bocsan, Ioana Corina
Safety of Vaccination within First Year of Life—The Experience of One General Medicine Center
title Safety of Vaccination within First Year of Life—The Experience of One General Medicine Center
title_full Safety of Vaccination within First Year of Life—The Experience of One General Medicine Center
title_fullStr Safety of Vaccination within First Year of Life—The Experience of One General Medicine Center
title_full_unstemmed Safety of Vaccination within First Year of Life—The Experience of One General Medicine Center
title_short Safety of Vaccination within First Year of Life—The Experience of One General Medicine Center
title_sort safety of vaccination within first year of life—the experience of one general medicine center
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856298/
https://www.ncbi.nlm.nih.gov/pubmed/36670654
http://dx.doi.org/10.3390/children10010104
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