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DNA Damage Response Alterations in Ovarian Cancer: From Molecular Mechanisms to Therapeutic Opportunities

SIMPLE SUMMARY: The DNA damage response (DDR) is frequently altered in ovarian cancer (OC), which can be exploited for therapeutic purposes. Moreover, targeting DDR signaling pathways has become an attractive strategy for increasing the effect of DNA-damaging drugs and overcoming chemoresistance. He...

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Detalles Bibliográficos
Autores principales: Ovejero-Sánchez, María, González-Sarmiento, Rogelio, Herrero, Ana Belén
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856346/
https://www.ncbi.nlm.nih.gov/pubmed/36672401
http://dx.doi.org/10.3390/cancers15020448