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Highly Metastatic Subpopulation of TNBC Cells Has Limited Iron Metabolism and Is a Target of Iron Chelators

SIMPLE SUMMARY: Excess iron is known to be a risk factor of carcinogenesis. Although iron chelators show anti-cancer effects, they have not been used successfully to treat cancer patients. Triple-negative breast cancer (TNBC) is a disease with poor prognosis without effective treatments. Thus, we ai...

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Detalles Bibliográficos
Autores principales: Wang, Yuze, Ohara, Toshiaki, Chen, Yuehua, Hamada, Yusuke, Li, Chunning, Fujisawa, Masayoshi, Yoshimura, Teizo, Matsukawa, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856351/
https://www.ncbi.nlm.nih.gov/pubmed/36672419
http://dx.doi.org/10.3390/cancers15020468