Advances in the Treatment of Pediatric Brain Tumors

Pediatric brain tumors are the most common solid malignancies in children. Advances in the treatment of pediatric brain tumors have come in the form of imaging, biopsy, surgical techniques, and molecular profiling. This has led the way for targeted therapies and immunotherapy to be assessed in clini...

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Autores principales: Kulubya, Edwin S., Kercher, Matthew J., Phillips, H. Westley, Antony, Reuben, Edwards, Michael S. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856380/
https://www.ncbi.nlm.nih.gov/pubmed/36670613
http://dx.doi.org/10.3390/children10010062
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author Kulubya, Edwin S.
Kercher, Matthew J.
Phillips, H. Westley
Antony, Reuben
Edwards, Michael S. B.
author_facet Kulubya, Edwin S.
Kercher, Matthew J.
Phillips, H. Westley
Antony, Reuben
Edwards, Michael S. B.
author_sort Kulubya, Edwin S.
collection PubMed
description Pediatric brain tumors are the most common solid malignancies in children. Advances in the treatment of pediatric brain tumors have come in the form of imaging, biopsy, surgical techniques, and molecular profiling. This has led the way for targeted therapies and immunotherapy to be assessed in clinical trials for the most common types of pediatric brain tumors. Here we review the latest efforts and challenges in targeted molecular therapy, immunotherapy, and newer modalities such as laser interstitial thermal therapy.
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spelling pubmed-98563802023-01-21 Advances in the Treatment of Pediatric Brain Tumors Kulubya, Edwin S. Kercher, Matthew J. Phillips, H. Westley Antony, Reuben Edwards, Michael S. B. Children (Basel) Review Pediatric brain tumors are the most common solid malignancies in children. Advances in the treatment of pediatric brain tumors have come in the form of imaging, biopsy, surgical techniques, and molecular profiling. This has led the way for targeted therapies and immunotherapy to be assessed in clinical trials for the most common types of pediatric brain tumors. Here we review the latest efforts and challenges in targeted molecular therapy, immunotherapy, and newer modalities such as laser interstitial thermal therapy. MDPI 2022-12-27 /pmc/articles/PMC9856380/ /pubmed/36670613 http://dx.doi.org/10.3390/children10010062 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Kulubya, Edwin S.
Kercher, Matthew J.
Phillips, H. Westley
Antony, Reuben
Edwards, Michael S. B.
Advances in the Treatment of Pediatric Brain Tumors
title Advances in the Treatment of Pediatric Brain Tumors
title_full Advances in the Treatment of Pediatric Brain Tumors
title_fullStr Advances in the Treatment of Pediatric Brain Tumors
title_full_unstemmed Advances in the Treatment of Pediatric Brain Tumors
title_short Advances in the Treatment of Pediatric Brain Tumors
title_sort advances in the treatment of pediatric brain tumors
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856380/
https://www.ncbi.nlm.nih.gov/pubmed/36670613
http://dx.doi.org/10.3390/children10010062
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