Analysis of Human Leukocyte Antigen DR Alleles, Immune-Related Adverse Events, and Survival Associated With Immune Checkpoint Inhibitor Use Among Patients With Advanced Malignant Melanoma

IMPORTANCE: Treatment with immune checkpoint inhibitors (ICIs) has increased survival in patients with advanced malignant melanoma but can be associated with a wide range of immune-related adverse events (irAEs). The role of human leukocyte antigen (HLA)–DR alleles in conferring irAE risk has not be...

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Detalles Bibliográficos
Autores principales: Akturk, Halis Kaan, Couts, Kasey L., Baschal, Erin E., Karakus, Kagan E., Van Gulick, Robert J., Turner, Jacqueline A., Pyle, Laura, Robinson, William A., Michels, Aaron W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2022
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856415/
https://www.ncbi.nlm.nih.gov/pubmed/36512357
http://dx.doi.org/10.1001/jamanetworkopen.2022.46400

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