Cargando…
Preclinical Evaluation of a Novel Small Molecule LCC-21 to Suppress Colorectal Cancer Malignancy by Inhibiting Angiogenic and Metastatic Signatures
Colorectal cancer (CRC) is one of the most common cancers, and it frequently metastasizes to the liver and lymph nodes. Despite major advances in treatment modalities, CRC remains a poorly characterized biological malignancy, with high reported cases of deaths globally. Moreover, cancer stem cells (...
Autores principales: | Mokgautsi, Ntlotlang, Kuo, Yu-Cheng, Huang, Yan-Jiun, Chen, Chien-Hsin, Mukhopadhyay, Debabrata, Wu, Alexander T. H., Huang, Hsu-Shan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856425/ https://www.ncbi.nlm.nih.gov/pubmed/36672201 http://dx.doi.org/10.3390/cells12020266 |
Ejemplares similares
-
Comprehensive Omics Analysis of a Novel Small-Molecule Inhibitor of Chemoresistant Oncogenic Signatures in Colorectal Cancer Cell with Antitumor Effects
por: Huang, Tse-Hung, et al.
Publicado: (2021) -
Multiomics Study of a Novel Naturally Derived Small Molecule, NSC772864, as a Potential Inhibitor of Proto-Oncogenes Regulating Cell Cycle Progression in Colorectal Cancer
por: Mokgautsi, Ntlotlang, et al.
Publicado: (2023) -
In Silico Evaluation of HN-N07 Small Molecule as an Inhibitor of Angiogenesis and Lymphangiogenesis Oncogenic Signatures in Non-Small Cell Lung Cancer
por: Chen, Lung-Ching, et al.
Publicado: (2023) -
Anticancer Activities of 9-chloro-6-(piperazin-1-yl)-11H-indeno[1,2-c] quinolin-11-one (SJ10) in Glioblastoma Multiforme (GBM) Chemoradioresistant Cell Cycle-Related Oncogenic Signatures
por: Mokgautsi, Ntlotlang, et al.
Publicado: (2022) -
Preclinical Identification of Sulfasalazine’s Therapeutic Potential for Suppressing Colorectal Cancer Stemness and Metastasis through Targeting KRAS/MMP7/CD44 Signaling
por: Leung, Wai-Hung, et al.
Publicado: (2022)