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3q26.2/MECOM Rearrangements by Pericentric Inv(3): Diagnostic Challenges and Clinicopathologic Features

SIMPLE SUMMARY: In this study, 17 acute myeloid leukemia (AML) patients were identified to pose a pericentric inv(3) aberration with breakpoints at 3p23 (n = 11), 3p25 (n = 3), 3p21 (n = 2) and 3p13 (n = 1) on 3p and 3q26.2 on 3q, leading to MECOM rearrangement (MECOM-R). These pericentric inv(3)s w...

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Detalles Bibliográficos
Autores principales: Tang, Zhenya, Wang, Wei, Yang, Su, El Achi, Hanadi, Fang, Hong, Nahmod, Karen Amelia, Toruner, Gokce A., Xu, Jie, Thakral, Beenu, Ayoub, Edward, Issa, Ghayas C., Yin, C. Cameron, You, M. James, Miranda, Roberto N., Khoury, Joseph D., Medeiros, L. Jeffrey, Tang, Guilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856433/
https://www.ncbi.nlm.nih.gov/pubmed/36672407
http://dx.doi.org/10.3390/cancers15020458