Current Advances in Technologies for Single Extracellular Vesicle Analysis and Its Clinical Applications in Cancer Diagnosis

Extracellular vesicles (EVs) have been regarded as one of the most potential diagnostic biomarkers for different cancers, due to their unique physiological and pathological functions. However, it is still challenging to precisely analyze the contents and sources of EVs, due to their heterogeneity. H...

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Detalles Bibliográficos
Autores principales: Qiu, Lei, Liu, Xingzhu, Zhu, Libo, Luo, Liqiang, Sun, Na, Pei, Renjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856491/
https://www.ncbi.nlm.nih.gov/pubmed/36671964
http://dx.doi.org/10.3390/bios13010129
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author Qiu, Lei
Liu, Xingzhu
Zhu, Libo
Luo, Liqiang
Sun, Na
Pei, Renjun
author_facet Qiu, Lei
Liu, Xingzhu
Zhu, Libo
Luo, Liqiang
Sun, Na
Pei, Renjun
author_sort Qiu, Lei
collection PubMed
description Extracellular vesicles (EVs) have been regarded as one of the most potential diagnostic biomarkers for different cancers, due to their unique physiological and pathological functions. However, it is still challenging to precisely analyze the contents and sources of EVs, due to their heterogeneity. Herein, we summarize the advances in technologies for a single EV analysis, which may provide new strategies to study the heterogeneity of EVs, as well as their cargo, more specifically. Furthermore, the applications of a single EV analysis on cancer early diagnosis are also discussed.
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spelling pubmed-98564912023-01-21 Current Advances in Technologies for Single Extracellular Vesicle Analysis and Its Clinical Applications in Cancer Diagnosis Qiu, Lei Liu, Xingzhu Zhu, Libo Luo, Liqiang Sun, Na Pei, Renjun Biosensors (Basel) Review Extracellular vesicles (EVs) have been regarded as one of the most potential diagnostic biomarkers for different cancers, due to their unique physiological and pathological functions. However, it is still challenging to precisely analyze the contents and sources of EVs, due to their heterogeneity. Herein, we summarize the advances in technologies for a single EV analysis, which may provide new strategies to study the heterogeneity of EVs, as well as their cargo, more specifically. Furthermore, the applications of a single EV analysis on cancer early diagnosis are also discussed. MDPI 2023-01-12 /pmc/articles/PMC9856491/ /pubmed/36671964 http://dx.doi.org/10.3390/bios13010129 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Qiu, Lei
Liu, Xingzhu
Zhu, Libo
Luo, Liqiang
Sun, Na
Pei, Renjun
Current Advances in Technologies for Single Extracellular Vesicle Analysis and Its Clinical Applications in Cancer Diagnosis
title Current Advances in Technologies for Single Extracellular Vesicle Analysis and Its Clinical Applications in Cancer Diagnosis
title_full Current Advances in Technologies for Single Extracellular Vesicle Analysis and Its Clinical Applications in Cancer Diagnosis
title_fullStr Current Advances in Technologies for Single Extracellular Vesicle Analysis and Its Clinical Applications in Cancer Diagnosis
title_full_unstemmed Current Advances in Technologies for Single Extracellular Vesicle Analysis and Its Clinical Applications in Cancer Diagnosis
title_short Current Advances in Technologies for Single Extracellular Vesicle Analysis and Its Clinical Applications in Cancer Diagnosis
title_sort current advances in technologies for single extracellular vesicle analysis and its clinical applications in cancer diagnosis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856491/
https://www.ncbi.nlm.nih.gov/pubmed/36671964
http://dx.doi.org/10.3390/bios13010129
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