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Concurrent Inhibition of Akt and ERK Using TIC-10 Can Overcome Venetoclax Resistance in Mantle Cell Lymphoma
SIMPLE SUMMARY: Targeting BCL-2 through venetoclax is an effective therapy for a series of hematological cancers, such as mantle cell lymphoma (MCL), but resistance to venetoclax is an increasing challenge that needs to be overcome. In order to elucidate the resistance mechanisms to venetoclax in MC...
Autores principales: | Granau, Agnete Marie, Andersen, Pilar Aarøe, Jakobsen, Theresa, Taouxi, Konstantina, Dalila, Nawar, Mogensen, Johanne Bay, Kristensen, Lasse Sommer, Grønbæk, Kirsten, Dimopoulos, Konstantinos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856512/ https://www.ncbi.nlm.nih.gov/pubmed/36672458 http://dx.doi.org/10.3390/cancers15020510 |
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