Dexamethasone-Induced Fatty Acid Oxidation and Autophagy/Mitophagy Are Essential for T-ALL Glucocorticoid Resistance

SIMPLE SUMMARY: Reduced response to glucocorticoids (GCs, such as dexamethasone, Dex), first-line drugs employed during therapy induction, is considered a poor prognosis factor for T-cell acute lymphoblastic leukemia (T-ALL) patients. Here, the effects of Dex in patient-derived T-ALL cell lines were...

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Detalles Bibliográficos
Autores principales: Olivas-Aguirre, Miguel, Pérez-Chávez, Jesús, Torres-López, Liliana, Hernández-Cruz, Arturo, Pottosin, Igor, Dobrovinskaya, Oxana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856638/
https://www.ncbi.nlm.nih.gov/pubmed/36672393
http://dx.doi.org/10.3390/cancers15020445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856638/
https://www.ncbi.nlm.nih.gov/pubmed/36672393
http://dx.doi.org/10.3390/cancers15020445

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