Cargando…
Multiple Copies of microRNA Binding Sites in Long 3′UTR Variants Regulate Axonal Translation
Rapid responses to changes within subcellular compartments of highly polarized cells, such as neuron axons, depend on local translation and post-transcriptional regulation. The mechanism by which microRNAs (miRNAs) regulate this process is not fully understood. Here, using live cell imaging and RNA...
Autores principales: | Farberov, Luba, Ionescu, Ariel, Zoabi, Yazeed, Shapira, Guy, Ibraheem, Amjd, Azan, Yosi, Perlson, Eran, Shomron, Noam |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856650/ https://www.ncbi.nlm.nih.gov/pubmed/36672174 http://dx.doi.org/10.3390/cells12020233 |
Ejemplares similares
-
mRNA splicing is modulated by intronic microRNAs
por: Farberov, Luba, et al.
Publicado: (2023) -
Axonal TDP-43 condensates drive neuromuscular junction disruption through inhibition of local synthesis of nuclear encoded mitochondrial proteins
por: Altman, Topaz, et al.
Publicado: (2021) -
Looking for answers far away from the soma—the (un)known axonal functions of TDP-43, and their contribution to early NMJ disruption in ALS
por: Ionescu, Ariel, et al.
Publicado: (2023) -
Co-transport of the nuclear-encoded Cox7c mRNA with mitochondria along axons occurs through a coding-region-dependent mechanism
por: Cohen, Bar, et al.
Publicado: (2022) -
The biomechanics of ultra-stretchable nerves
por: Das, Rakesh, et al.
Publicado: (2022)