Cargando…

Effect of Intermediate Airway Management on Ventilation Parameters in Simulated Pediatric Out-of-Hospital Cardiac Arrest: Protocol for a Multicenter, Randomized, Crossover Trial

Most pediatric out-of-hospital cardiac arrests (OHCAs) are caused by hypoxia, which is generally consecutive to respiratory failure. To restore oxygenation, prehospital providers usually first use basic airway management techniques, i.e., bag-valve-mask (BVM) devices. These devices present several d...

Descripción completa

Detalles Bibliográficos
Autores principales: Stuby, Loric, Mühlemann, Elisa, Jampen, Laurent, Thurre, David, Siebert, Johan N., Suppan, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856669/
https://www.ncbi.nlm.nih.gov/pubmed/36670698
http://dx.doi.org/10.3390/children10010148
_version_ 1784873689793167360
author Stuby, Loric
Mühlemann, Elisa
Jampen, Laurent
Thurre, David
Siebert, Johan N.
Suppan, Laurent
author_facet Stuby, Loric
Mühlemann, Elisa
Jampen, Laurent
Thurre, David
Siebert, Johan N.
Suppan, Laurent
author_sort Stuby, Loric
collection PubMed
description Most pediatric out-of-hospital cardiac arrests (OHCAs) are caused by hypoxia, which is generally consecutive to respiratory failure. To restore oxygenation, prehospital providers usually first use basic airway management techniques, i.e., bag-valve-mask (BVM) devices. These devices present several drawbacks, most of which could be avoided using supraglottic airway devices. These intermediate airway management (IAM) devices also present significant advantages over tracheal intubation: they are associated with higher success and lower complication rates in the prehospital setting. There are, however, few data regarding the effect of early IAM in pediatric OHCA. This paper details the protocol of a trial designed to evaluate the impact of this airway management strategy on ventilation parameters through a simulated, multicenter, randomized, crossover trial. The hypothesis underlying this study protocol is that early IAM without prior BVM ventilations could improve the ventilation parameters in comparison with the standard approach, which consists in BVM ventilations only.
format Online
Article
Text
id pubmed-9856669
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-98566692023-01-21 Effect of Intermediate Airway Management on Ventilation Parameters in Simulated Pediatric Out-of-Hospital Cardiac Arrest: Protocol for a Multicenter, Randomized, Crossover Trial Stuby, Loric Mühlemann, Elisa Jampen, Laurent Thurre, David Siebert, Johan N. Suppan, Laurent Children (Basel) Study Protocol Most pediatric out-of-hospital cardiac arrests (OHCAs) are caused by hypoxia, which is generally consecutive to respiratory failure. To restore oxygenation, prehospital providers usually first use basic airway management techniques, i.e., bag-valve-mask (BVM) devices. These devices present several drawbacks, most of which could be avoided using supraglottic airway devices. These intermediate airway management (IAM) devices also present significant advantages over tracheal intubation: they are associated with higher success and lower complication rates in the prehospital setting. There are, however, few data regarding the effect of early IAM in pediatric OHCA. This paper details the protocol of a trial designed to evaluate the impact of this airway management strategy on ventilation parameters through a simulated, multicenter, randomized, crossover trial. The hypothesis underlying this study protocol is that early IAM without prior BVM ventilations could improve the ventilation parameters in comparison with the standard approach, which consists in BVM ventilations only. MDPI 2023-01-12 /pmc/articles/PMC9856669/ /pubmed/36670698 http://dx.doi.org/10.3390/children10010148 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Study Protocol
Stuby, Loric
Mühlemann, Elisa
Jampen, Laurent
Thurre, David
Siebert, Johan N.
Suppan, Laurent
Effect of Intermediate Airway Management on Ventilation Parameters in Simulated Pediatric Out-of-Hospital Cardiac Arrest: Protocol for a Multicenter, Randomized, Crossover Trial
title Effect of Intermediate Airway Management on Ventilation Parameters in Simulated Pediatric Out-of-Hospital Cardiac Arrest: Protocol for a Multicenter, Randomized, Crossover Trial
title_full Effect of Intermediate Airway Management on Ventilation Parameters in Simulated Pediatric Out-of-Hospital Cardiac Arrest: Protocol for a Multicenter, Randomized, Crossover Trial
title_fullStr Effect of Intermediate Airway Management on Ventilation Parameters in Simulated Pediatric Out-of-Hospital Cardiac Arrest: Protocol for a Multicenter, Randomized, Crossover Trial
title_full_unstemmed Effect of Intermediate Airway Management on Ventilation Parameters in Simulated Pediatric Out-of-Hospital Cardiac Arrest: Protocol for a Multicenter, Randomized, Crossover Trial
title_short Effect of Intermediate Airway Management on Ventilation Parameters in Simulated Pediatric Out-of-Hospital Cardiac Arrest: Protocol for a Multicenter, Randomized, Crossover Trial
title_sort effect of intermediate airway management on ventilation parameters in simulated pediatric out-of-hospital cardiac arrest: protocol for a multicenter, randomized, crossover trial
topic Study Protocol
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856669/
https://www.ncbi.nlm.nih.gov/pubmed/36670698
http://dx.doi.org/10.3390/children10010148
work_keys_str_mv AT stubyloric effectofintermediateairwaymanagementonventilationparametersinsimulatedpediatricoutofhospitalcardiacarrestprotocolforamulticenterrandomizedcrossovertrial
AT muhlemannelisa effectofintermediateairwaymanagementonventilationparametersinsimulatedpediatricoutofhospitalcardiacarrestprotocolforamulticenterrandomizedcrossovertrial
AT jampenlaurent effectofintermediateairwaymanagementonventilationparametersinsimulatedpediatricoutofhospitalcardiacarrestprotocolforamulticenterrandomizedcrossovertrial
AT thurredavid effectofintermediateairwaymanagementonventilationparametersinsimulatedpediatricoutofhospitalcardiacarrestprotocolforamulticenterrandomizedcrossovertrial
AT siebertjohann effectofintermediateairwaymanagementonventilationparametersinsimulatedpediatricoutofhospitalcardiacarrestprotocolforamulticenterrandomizedcrossovertrial
AT suppanlaurent effectofintermediateairwaymanagementonventilationparametersinsimulatedpediatricoutofhospitalcardiacarrestprotocolforamulticenterrandomizedcrossovertrial