TGFβ1-Induced EMT in the MCF10A Mammary Epithelial Cell Line Model Is Executed Independently of SNAIL1 and ZEB1 but Relies on JUNB-Coordinated Transcriptional Regulation

SIMPLE SUMMARY: While invading tumor-adjacent tissue, cancer cells often undergo epithelial-mesenchymal transition (EMT). A mechanistic understanding of EMT may therefore improve diagnostic and therapeutic options. Traditionally, EMT is thought to be regulated by SNAIL, TWIST, and ZEB transcription...

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Detalles Bibliográficos
Autores principales: Antón-García, Pablo, Haghighi, Elham Bavafaye, Rose, Katja, Vladimirov, Georg, Boerries, Melanie, Hecht, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856774/
https://www.ncbi.nlm.nih.gov/pubmed/36672507
http://dx.doi.org/10.3390/cancers15020558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856774/
https://www.ncbi.nlm.nih.gov/pubmed/36672507
http://dx.doi.org/10.3390/cancers15020558

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