NEK6 Regulates Redox Balance and DNA Damage Response in DU-145 Prostate Cancer Cells

NEK6 is a central kinase in developing castration-resistant prostate cancer (CRPC). However, the pathways regulated by NEK6 in CRPC are still unclear. Cancer cells have high reactive oxygen species (ROS) levels and easily adapt to this circumstance and avoid cell death by increasing antioxidant defe...

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Detalles Bibliográficos
Autores principales: Pavan, Isadora Carolina Betim, Basei, Fernanda Luisa, Severino, Matheus Brandemarte, Rosa e Silva, Ivan, Issayama, Luidy Kazuo, Mancini, Mariana Camargo Silva, Góis, Mariana Marcela, da Silva, Luiz Guilherme Salvino, Bezerra, Rosangela Maria Neves, Simabuco, Fernando Moreira, Kobarg, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856815/
https://www.ncbi.nlm.nih.gov/pubmed/36672191
http://dx.doi.org/10.3390/cells12020256

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