Cargando…

Myelination generates aberrant ultrastructure that is resolved by microglia

To enable rapid propagation of action potentials, axons are ensheathed by myelin, a multilayered insulating membrane formed by oligodendrocytes. Most of the myelin is generated early in development, resulting in the generation of long-lasting stable membrane structures. Here, we explored structural...

Descripción completa

Detalles Bibliográficos
Autores principales:	Djannatian, Minou, Radha, Swathi, Weikert, Ulrich, Safaiyan, Shima, Wrede, Christoph, Deichsel, Cassandra, Kislinger, Georg, Rhomberg, Agata, Ruhwedel, Torben, Campbell, Douglas S., van Ham, Tjakko, Schmid, Bettina, Hegermann, Jan, Möbius, Wiebke, Schifferer, Martina, Simons, Mikael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856851/ https://www.ncbi.nlm.nih.gov/pubmed/36637807 http://dx.doi.org/10.1083/jcb.202204010

Ejemplares similares

Two adhesive systems cooperatively regulate axon ensheathment and myelin growth in the CNS
por: Djannatian, Minou, et al.
Publicado: (2019)

Pro-inflammatory activation following demyelination is required for myelin clearance and oligodendrogenesis
por: Cunha, Maria Inês, et al.
Publicado: (2020)

New Species Can Broaden Myelin Research: Suitability of Little Skate, Leucoraja erinacea
por: Möbius, Wiebke, et al.
Publicado: (2021)

Ganglioside lipidomics of CNS myelination using direct infusion shotgun mass spectrometry
por: Arends, Martina, et al.
Publicado: (2022)

Multiscale ATUM-FIB Microscopy Enables Targeted Ultrastructural Analysis at Isotropic Resolution
por: Kislinger, Georg, et al.
Publicado: (2020)

Niwaki Instead of Random Forests: Targeted Serial Sectioning Scanning Electron Microscopy With Reimaging Capabilities for Exploring Central Nervous System Cell Biology and Pathology
por: Schifferer, Martina, et al.
Publicado: (2021)

Loss of Myelin Basic Protein Function Triggers Myelin Breakdown in Models of Demyelinating Diseases
por: Weil, Marie-Theres, et al.
Publicado: (2016)

Pathology of myelinated axons in the PLP-deficient mouse model of spastic paraplegia type 2 revealed by volume imaging using focused ion beam-scanning electron microscopy
por: Steyer, Anna M., et al.
Publicado: (2020)

Cortical network dysfunction caused by a subtle defect of myelination
por: Poggi, Giulia, et al.
Publicado: (2016)

Intranasal mesenchymal stem cell therapy to boost myelination after encephalopathy of prematurity
por: Vaes, Josine E. G., et al.
Publicado: (2020)

White matter integrity in mice requires continuous myelin synthesis at the inner tongue
por: Meschkat, Martin, et al.
Publicado: (2022)

ATUM-FIB microscopy for targeting and multiscale imaging of rare events in mouse cortex
por: Kislinger, Georg, et al.
Publicado: (2020)

Neuronal activity disrupts myelinated axon integrity in the absence of NKCC1b
por: Marshall-Phelps, Katy L.H., et al.
Publicado: (2020)

Progressive axonopathy when oligodendrocytes lack the myelin protein CMTM5
por: Buscham, Tobias J, et al.
Publicado: (2022)

Ketogenic diet ameliorates axonal defects and promotes myelination in Pelizaeus–Merzbacher disease
por: Stumpf, Sina K., et al.
Publicado: (2019)

Lack of astrocytes hinders parenchymal oligodendrocyte precursor cells from reaching a myelinating state in osmolyte-induced demyelination
por: Lohrberg, Melanie, et al.
Publicado: (2020)

Correction to: Ketogenic diet ameliorates axonal defects and promotes myelination in Pelizaeus–Merzbacher disease
por: Stumpf, Sina K., et al.
Publicado: (2019)

The Axon-Myelin Unit in Development and Degenerative Disease
por: Stassart, Ruth M., et al.
Publicado: (2018)

Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s disease
por: Depp, Constanze, et al.
Publicado: (2023)

Convergent evolution of the sensory pits in and within flatworms
por: Gąsiorowski, Ludwik, et al.
Publicado: (2023)

Antagonistic Functions of MBP and CNP Establish Cytosolic Channels in CNS Myelin
por: Snaidero, Nicolas, et al.
Publicado: (2017)

Proteome Profile of Myelin in the Zebrafish Brain
por: Siems, Sophie B., et al.
Publicado: (2021)

Myelin replacement triggered by single-cell demyelination in mouse cortex
por: Snaidero, Nicolas, et al.
Publicado: (2020)

REDUNDANT MYELIN SHEATHS AND OTHER ULTRASTRUCTURAL FEATURES OF THE TOAD CEREBELLUM
por: Rosenbluth, Jack
Publicado: (1966)

Aspartoacylase-LacZ Knockin Mice: An Engineered Model of Canavan Disease
por: Mersmann, Nadine, et al.
Publicado: (2011)

Blood-brain barrier hyperpermeability precedes demyelination in the cuprizone model
por: Berghoff, Stefan A., et al.
Publicado: (2017)

ULTRASTRUCTURAL LOCALIZATION OF PHOSPHOLIPID SYNTHESIS IN THE RAT TRIGEMINAL NERVE DURING MYELINATION
por: Benes, Francine, et al.
Publicado: (1973)

THE ULTRASTRUCTURE OF ADULT VERTEBRATE PERIPHERAL MYELINATED NERVE FIBERS IN RELATION TO MYELINOGENESIS
por: Robertson, J. David
Publicado: (1955)

The Ultrastructure of Schmidt-Lanterman Clefts and Related Shearing Defects of the Myelin Sheath
por: Robertson, J. David
Publicado: (1958)

Spatial Transcriptomics-correlated Electron Microscopy maps transcriptional and ultrastructural responses to brain injury
por: Androvic, Peter, et al.
Publicado: (2023)

Tuning PAK Activity to Rescue Abnormal Myelin Permeability in HNPP
por: Hu, Bo, et al.
Publicado: (2016)

Volume electron microscopy: analyzing the lung
por: Schneider, Jan Philipp, et al.
Publicado: (2020)

Erythropoietin treatment alleviates ultrastructural myelin changes induced by murine cerebral malaria
por: Hempel, Casper, et al.
Publicado: (2012)

Saltatory Conduction along Myelinated Axons Involves a Periaxonal Nanocircuit
por: Cohen, Charles C.H., et al.
Publicado: (2020)

BACE1 Processing of NRG1 Type III Produces a Myelin-Inducing Signal but Is Not Essential for the Stimulation of Myelination
por: Velanac, Viktorija, et al.
Publicado: (2012)

STUDIES ON THE PROBLEM OF PRESERVATION OF MYELIN SHEATH ULTRASTRUCTURE: EVALUATION OF FIXATION, DEHYDRATION, AND EMBEDDING TECHNIQUES
por: Condie, Richard M., et al.
Publicado: (1961)

Ultrastructural study of myelinating cells and sub-pial astrocytes in developing rat spinal cord()
por: Nagashima, Kazuo
Publicado: (1979)

Oligodendrocyte ablation triggers central pain independently of innate or adaptive immune responses in mice
por: Gritsch, Simon, et al.
Publicado: (2014)

Septin/anillin filaments scaffold central nervous system myelin to accelerate nerve conduction
por: Patzig, Julia, et al.
Publicado: (2016)

Improvement of different vaccine delivery systems for cancer therapy
por: Bolhassani, Azam, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_0liuvu6iocdscqqpogdiar555i