Rescue of Mitochondrial Function in Hutchinson-Gilford Progeria Syndrome by the Pharmacological Modulation of Exportin CRM1

Hutchinson-Gilford progeria syndrome (HGPS) is a rare premature aging disorder caused by the expression of progerin, a mutant variant of Lamin A. Recently, HGPS studies have gained relevance because unraveling its underlying mechanism would help to understand physiological aging. We previously repor...

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Detalles Bibliográficos
Autores principales: Monterrubio-Ledezma, Feliciano, Navarro-García, Fernando, Massieu, Lourdes, Mondragón-Flores, Ricardo, Soto-Ponce, Luz Adriana, Magaña, Jonathan J., Cisneros, Bulmaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856861/
https://www.ncbi.nlm.nih.gov/pubmed/36672210
http://dx.doi.org/10.3390/cells12020275

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