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Association of Maternal and Paternal Astigmatism With Child Astigmatism in the Hong Kong Children Eye Study

IMPORTANCE: Parental astigmatism is a factor associated with risk for development of child astigmatism; however, the magnitude of the association has not been determined. OBJECTIVE: To determine the association between parental and child astigmatism. DESIGN, SETTING, AND PARTICIPANTS: This populatio...

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Autores principales: Kam, Ka Wai, Chee, Arnold S. H., Zhang, Yuzhou, Tang, Rex C. Y., Chan, Jason T. C., Zhang, Xiu Juan, Wang, Yu Meng, Chan, Ryan C. F., Chu, Wai Kit, Ip, Patrick, Young, Alvin L., Tham, Clement C., Pang, Chi Pui, Chen, Li Jia, Yam, Jason C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856878/
https://www.ncbi.nlm.nih.gov/pubmed/36542383
http://dx.doi.org/10.1001/jamanetworkopen.2022.47795
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author Kam, Ka Wai
Chee, Arnold S. H.
Zhang, Yuzhou
Tang, Rex C. Y.
Chan, Jason T. C.
Zhang, Xiu Juan
Wang, Yu Meng
Chan, Ryan C. F.
Chu, Wai Kit
Ip, Patrick
Young, Alvin L.
Tham, Clement C.
Pang, Chi Pui
Chen, Li Jia
Yam, Jason C.
author_facet Kam, Ka Wai
Chee, Arnold S. H.
Zhang, Yuzhou
Tang, Rex C. Y.
Chan, Jason T. C.
Zhang, Xiu Juan
Wang, Yu Meng
Chan, Ryan C. F.
Chu, Wai Kit
Ip, Patrick
Young, Alvin L.
Tham, Clement C.
Pang, Chi Pui
Chen, Li Jia
Yam, Jason C.
author_sort Kam, Ka Wai
collection PubMed
description IMPORTANCE: Parental astigmatism is a factor associated with risk for development of child astigmatism; however, the magnitude of the association has not been determined. OBJECTIVE: To determine the association between parental and child astigmatism. DESIGN, SETTING, AND PARTICIPANTS: This population-based, cross-sectional study included participants from familial trios, each comprising a child aged 6 to 8 years and both parents, recruited from the Hong Kong Children Eye Study. No restriction criteria were set on the children in terms of refractive status. Data were analyzed from February to June 2022. EXPOSURES: Cycloplegic autorefraction and autokeratometry were conducted on the children, whereas noncycloplegic autorefraction and autokeratometry were conducted on their parents. The children were categorized into 6 groups on the basis of the severity of astigmatism of both parents. Information on parental education, family income, and children’s outdoor and near work time were obtained by questionnaires. MAIN OUTCOMES AND MEASURES: The primary outcome was the odds of child astigmatism among the 6 categories of children. Associations of factors with child astigmatism were evaluated by logistic regression analyses. RESULTS: A total of 17 124 participants from 5708 trios (2964 boys and 2754 girls) at a mean (SD) age of 7.32 (0.87) years, and 11 416 parents were examined. Astigmatism of 1.0 D or greater in both parents was associated with greater odds of refractive astigmatism (RA) (odds ratio [OR], 1.62; 95% CI, 1.15-2.26) and corneal astigmatism (CA) (OR, 1.94; 95% CI, 1.50-2.50) in the child. The respective ORs increased to 3.10 (95% CI, 1.34-7.21) and 4.31 (95% CI, 1.76-10.55) when both parents had astigmatism 2.0 D or greater. Higher parental astigmatism conferred higher risks for both RA and CA in children (P for trend <.001). Parental astigmatism was significantly associated with greater odds of corresponding child astigmatism (maternal RA: OR, 0.76; 95% CI, 0.68-0.84; paternal RA: OR, 0.82; 95% CI, 0.74-0.91; maternal CA: OR, 1.70; 95% CI, 1.51-1.93; paternal CA: OR, 1.33; 95% CI, 1.19-1.49). CONCLUSIONS AND RELEVANCE: The findings of this cross-sectional study suggest that parental astigmatism may confer an independent and dose-dependent association with child astigmatism. Children with parents with astigmatism should have early eye examinations for timely detection of astigmatism to facilitate age-appropriate vision correction and visual development.
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spelling pubmed-98568782023-02-03 Association of Maternal and Paternal Astigmatism With Child Astigmatism in the Hong Kong Children Eye Study Kam, Ka Wai Chee, Arnold S. H. Zhang, Yuzhou Tang, Rex C. Y. Chan, Jason T. C. Zhang, Xiu Juan Wang, Yu Meng Chan, Ryan C. F. Chu, Wai Kit Ip, Patrick Young, Alvin L. Tham, Clement C. Pang, Chi Pui Chen, Li Jia Yam, Jason C. JAMA Netw Open Original Investigation IMPORTANCE: Parental astigmatism is a factor associated with risk for development of child astigmatism; however, the magnitude of the association has not been determined. OBJECTIVE: To determine the association between parental and child astigmatism. DESIGN, SETTING, AND PARTICIPANTS: This population-based, cross-sectional study included participants from familial trios, each comprising a child aged 6 to 8 years and both parents, recruited from the Hong Kong Children Eye Study. No restriction criteria were set on the children in terms of refractive status. Data were analyzed from February to June 2022. EXPOSURES: Cycloplegic autorefraction and autokeratometry were conducted on the children, whereas noncycloplegic autorefraction and autokeratometry were conducted on their parents. The children were categorized into 6 groups on the basis of the severity of astigmatism of both parents. Information on parental education, family income, and children’s outdoor and near work time were obtained by questionnaires. MAIN OUTCOMES AND MEASURES: The primary outcome was the odds of child astigmatism among the 6 categories of children. Associations of factors with child astigmatism were evaluated by logistic regression analyses. RESULTS: A total of 17 124 participants from 5708 trios (2964 boys and 2754 girls) at a mean (SD) age of 7.32 (0.87) years, and 11 416 parents were examined. Astigmatism of 1.0 D or greater in both parents was associated with greater odds of refractive astigmatism (RA) (odds ratio [OR], 1.62; 95% CI, 1.15-2.26) and corneal astigmatism (CA) (OR, 1.94; 95% CI, 1.50-2.50) in the child. The respective ORs increased to 3.10 (95% CI, 1.34-7.21) and 4.31 (95% CI, 1.76-10.55) when both parents had astigmatism 2.0 D or greater. Higher parental astigmatism conferred higher risks for both RA and CA in children (P for trend <.001). Parental astigmatism was significantly associated with greater odds of corresponding child astigmatism (maternal RA: OR, 0.76; 95% CI, 0.68-0.84; paternal RA: OR, 0.82; 95% CI, 0.74-0.91; maternal CA: OR, 1.70; 95% CI, 1.51-1.93; paternal CA: OR, 1.33; 95% CI, 1.19-1.49). CONCLUSIONS AND RELEVANCE: The findings of this cross-sectional study suggest that parental astigmatism may confer an independent and dose-dependent association with child astigmatism. Children with parents with astigmatism should have early eye examinations for timely detection of astigmatism to facilitate age-appropriate vision correction and visual development. American Medical Association 2022-12-21 /pmc/articles/PMC9856878/ /pubmed/36542383 http://dx.doi.org/10.1001/jamanetworkopen.2022.47795 Text en Copyright 2022 Kam KW et al. JAMA Network Open. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the CC-BY License.
spellingShingle Original Investigation
Kam, Ka Wai
Chee, Arnold S. H.
Zhang, Yuzhou
Tang, Rex C. Y.
Chan, Jason T. C.
Zhang, Xiu Juan
Wang, Yu Meng
Chan, Ryan C. F.
Chu, Wai Kit
Ip, Patrick
Young, Alvin L.
Tham, Clement C.
Pang, Chi Pui
Chen, Li Jia
Yam, Jason C.
Association of Maternal and Paternal Astigmatism With Child Astigmatism in the Hong Kong Children Eye Study
title Association of Maternal and Paternal Astigmatism With Child Astigmatism in the Hong Kong Children Eye Study
title_full Association of Maternal and Paternal Astigmatism With Child Astigmatism in the Hong Kong Children Eye Study
title_fullStr Association of Maternal and Paternal Astigmatism With Child Astigmatism in the Hong Kong Children Eye Study
title_full_unstemmed Association of Maternal and Paternal Astigmatism With Child Astigmatism in the Hong Kong Children Eye Study
title_short Association of Maternal and Paternal Astigmatism With Child Astigmatism in the Hong Kong Children Eye Study
title_sort association of maternal and paternal astigmatism with child astigmatism in the hong kong children eye study
topic Original Investigation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9856878/
https://www.ncbi.nlm.nih.gov/pubmed/36542383
http://dx.doi.org/10.1001/jamanetworkopen.2022.47795
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